Global Applied Science Laboratory, GE Healthcare, Madison, WI 53705, USA.
J Magn Reson Imaging. 2013 Sep;38(3):751-6. doi: 10.1002/jmri.24018. Epub 2013 Jan 24.
To demonstrate the feasibility of performing single breathhold, noncardiac gated, ultrafast, high spatial-temporal resolution whole chest MR pulmonary perfusion imaging in humans.
Eight subjects (five male, three female) were scanned with the proposed method on a 3 Tesla clinical scanner using a 32-channel phased-array coil. Seven (88%) were healthy volunteers, and one was a patient volunteer with sarcoidosis. The peak lung enhancement phase for each subject was scored for gravitational effect, peak parenchymal enhancement and severity of artifacts by three cardiothoracic radiologists independently.
All studies were successfully performed by MR technologists without any additional training. Mean parenchymal signal was very good, measuring 0.78 ± 0.13 (continuous scale, 0 = "none" → 1 = "excellent"). Mean level of motion artifacts was low, measuring 0.13 ± 0.08 (continuous scale, 0 = "none" → 1 = "severe").
It is feasible to perform single breathhold, noncardiac gated, ultrafast, high spatial-temporal resolution whole chest MR pulmonary perfusion imaging in humans.
展示在人体上进行单次屏气、非心脏门控、超快、高时空分辨率全胸部 MR 肺灌注成像的可行性。
8 名受试者（5 名男性，3 名女性）在 3T 临床扫描仪上使用 32 通道相控阵线圈进行了该方法的扫描。其中 7 名（88%）为健康志愿者，1 名患有结节病的患者志愿者。3 名心胸放射科医生独立对每位受试者的肺部增强峰值期的重力效应、实质增强峰值和伪影严重程度进行评分。
所有研究均由磁共振技术人员成功完成，无需额外培训。平均实质信号非常好，测量值为 0.78 ± 0.13（连续量表，0 = “无”→1 = “优秀”）。平均运动伪影水平较低，测量值为 0.13 ± 0.08（连续量表，0 = “无”→1 = “严重”）。
在人体上进行单次屏气、非心脏门控、超快、高时空分辨率全胸部 MR 肺灌注成像的方法是可行的。
