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[清醒状态下的“丘脑-大脑皮层”解剖功能单元]

[The "thalamus-cerebral cortex" anatomofunctinal unit in the waking state].

作者信息

Reinoso Suárez Fernando

出版信息

An R Acad Nac Med (Madr). 2011;128(2):285-300; discussion 300-2.

PMID:23350331
Abstract

The "thalamus-cerebral cortex unit" is awakened by the "ascending reticular activating system", which originates from neuronal groups located within the brainstem, hypothalamus and basal forebrain, all of which use known neurotransmitters and whose neurons are more active during wakefulness than during the other behavioral states. Synergies among several of these neurotransmitters are necessary to generate the cortical and thalamic activation that is characteristic of wakefulness. During the wakefulness the complex interrelated structures of the "thalamus-cerebral cortex unit" provide the pathway that interconnects cortex and thalamus and allow the modulation, and organization of the mechanisms producing the adequate activity of the different thalamic and cortical formations and the organization of cognitive processes and performance of appropriate behavioral responses.

摘要

“丘脑 - 大脑皮层单元”由“上行网状激活系统”唤醒,该系统起源于位于脑干、下丘脑和基底前脑的神经元群,所有这些神经元群都使用已知的神经递质,并且其神经元在清醒状态下比在其他行为状态下更活跃。这些神经递质中的几种之间的协同作用对于产生清醒状态所特有的皮层和丘脑激活是必要的。在清醒状态下,“丘脑 - 大脑皮层单元”的复杂相互关联结构提供了连接皮层和丘脑的通路,并允许对产生不同丘脑和皮层结构适当活动的机制进行调节和组织,以及对认知过程进行组织和做出适当的行为反应。

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