Engels Paul T, Passos Edward, Beckett Andrew N, Doyle Jeffrey D, Tien Homer C
Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada; Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Injury. 2014 Jan;45(1):77-82. doi: 10.1016/j.injury.2012.12.026. Epub 2013 Jan 24.
Exsanguinating haemorrhage is a leading cause of death in severely injured trauma patients. Management includes achieving haemostasis, replacing lost intravascular volume with fluids and blood, and treating coagulopathy. The provision of fluids and blood products is contingent on obtaining adequate vascular access to the patient's venous system. We sought to examine the nature and timing of achieving adequate intravenous (IV) access in trauma patients requiring uncrossmatched blood in the trauma bay.
We performed a retrospective chart review of all patients admitted to our trauma centre from 2005 to 2009 who were transfused uncrossmatched blood in the trauma bay. We examined the impact of IV access on prehospital times and time to first PRBC transfusion.
Of 208 study patients, 168 (81%) received prehospital IV access, and the on-scene time for these patients was 5 min longer (16.1 vs 11.4, p<0.01). Time to achieving adequate IV access in those without any prehospital IVs occurred on average 21 min (6.6-30.5) after arrival to the trauma bay. A central venous catheter was placed in 92 (44%) of patients. Time to first blood transfusion correlated most strongly with time to achieving central venous access (Pearson correlation coefficient 0.94, p<0.001) as opposed to time to achieving adequate peripheral IV access (Pearson correlation coefficient 0.19, p=0.12).
We found that most bleeding patients received a prehospital IV; however, we also found that obtaining prehospital IVs was associated with longer EMS on-scene times and longer prehospital times. Interestingly, we found that obtaining a prehospital IV was not associated with more rapid initiation of blood product transfusion. Obtaining optimal IV access and subsequent blood transfusion in severely injured patients continues to present a challenge.
失血性出血是严重创伤患者死亡的主要原因。治疗措施包括实现止血、用液体和血液补充丢失的血管内容量以及治疗凝血功能障碍。液体和血液制品的供应取决于能否获得足够的血管通路以进入患者的静脉系统。我们试图研究在创伤病房需要输注未交叉配血的创伤患者中,获得足够静脉(IV)通路的性质和时机。
我们对2005年至2009年入住我们创伤中心且在创伤病房输注未交叉配血的所有患者进行了回顾性病历审查。我们研究了静脉通路对院前时间和首次输注红细胞悬液时间的影响。
在208例研究患者中,168例(81%)在院前获得了静脉通路,这些患者的现场时间长5分钟(16.1对11.4,p<0.01)。在那些院前没有静脉通路的患者中,平均在到达创伤病房后21分钟(6.6 - 30.5)获得足够的静脉通路。92例(44%)患者放置了中心静脉导管。首次输血时间与获得中心静脉通路的时间相关性最强(Pearson相关系数0.94,p<0.001),而与获得足够外周静脉通路的时间相关性较弱(Pearson相关系数0.19,p = 0.12)。
我们发现大多数出血患者在院前获得了静脉通路;然而,我们也发现获得院前静脉通路与更长的急救医疗服务现场时间和更长的院前时间相关。有趣的是,我们发现获得院前静脉通路与更快开始输注血液制品无关。在严重受伤患者中获得最佳静脉通路及随后的输血仍然是一项挑战。