Takeda Shu
Department of Internal Medicine, Keio University, Japan.
Clin Calcium. 2013 Feb;23(2):173-9.
The discovery that leptin regulates bone formation through the central nervous system shed light on a new regulatory system of bone metabolism, i.e., neuronal control. Of note, sympathetic nervous system and parasympathetic nervous system are intimately involved in bone remodeling separately and also in a coordinated manner. Moreover, orexigenic and anorexigenic peptides also regulate bone remodeling in various ways.
瘦素通过中枢神经系统调节骨形成这一发现揭示了骨代谢的一种新调节系统，即神经控制。值得注意的是，交感神经系统和副交感神经系统分别且协同密切参与骨重塑。此外，促食欲肽和抑食欲肽也以多种方式调节骨重塑。
