Michaud C R, Ragland D R, St Claire M C, Elkins W R, Gozalo A S
Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
J Comp Pathol. 2013 Aug-Oct;149(2-3):376-80. doi: 10.1016/j.jcpa.2012.12.001. Epub 2013 Jan 26.
A 2-year-old, captive-born, male moustached tamarin was subjected to necropsy examination after a fatal head trauma. A solitary, circumscribed, subpleural mass (0.6 cm diameter) was found in the right caudal lung lobe. The mass was diagnosed as a mucinous cystadenoma. Histochemical and immunohistochemical tests were performed to further characterize the tumour. Surfactant proteins A, B, C and D were not found in the neoplastic cells, suggesting that the tumour arose from a non-surfactant-producing alveolar lining cell. Pulmonary mucinous cystadenomas are uncommon benign tumours in man and have not been reported previously in animals.
一只圈养出生的2岁雄性髭狨猴在遭受致命头部创伤后进行了尸检。在右尾肺叶发现一个孤立的、边界清晰的胸膜下肿块(直径0.6厘米)。该肿块被诊断为黏液性囊腺瘤。进行了组织化学和免疫组织化学检测以进一步明确肿瘤特征。在肿瘤细胞中未发现表面活性蛋白A、B、C和D,提示该肿瘤起源于非表面活性物质产生的肺泡衬里细胞。肺黏液性囊腺瘤在人类中是罕见的良性肿瘤,此前在动物中未见报道。