Department of Radiology, Haseki Training and Research Hospital, 34096 Aksaray, Istanbul, Turkey.
Eur J Radiol. 2013 Aug;82(8):1248-54. doi: 10.1016/j.ejrad.2012.12.022. Epub 2013 Jan 26.
Radiologists and other clinicians are facing an increasing number of illegal drug-related medical conditions. We aimed to draw attention to this growing global problem and to highlight some of the important points related to diagnosis and follow-up of body packing. We compare the diagnostic performance of unenhanced multidetector CT (MDCT) and abdomen X-ray for the detection of drug-filled packets.
Sixty-seven suspects, who underwent both CT and X-ray examinations, have been included in the study. All MDCT and X-ray images were independently and retrospectively reviewed by two observers with different degrees of experience in abdomen imaging. Fifty-two of them were identified as body packers finally. Interobserver agreement, sensitivity, specificity, positive and negative predictive value were calculated.
Two types of packets with different characteristics were identified in all body packers. Type 1 packets (solid-state drug) were found in 41 patients and type 2 packets (liquid cocaine) in 11 patients. All statistical analyses concern the detection of any packets. That is, the whole evaluation has been performed per patient. Sensitivity/specificity values of type 1 and type 2 packets for MDCT were 100-98%/100-100% and 100-100%/100-100%, respectively. Besides, sensitivity/specificity values of type 1 and type 2 packets for X-ray were 93-90%/100-91% and 64-45%/73-71%, respectively. In addition, interobserver agreements for detection of any packets were excellent (κ=0.96) and good (κ=0.75) for interpretation of MDCT and X-ray, respectively.
Unenhanced MDCT is a fast, accurate and easily used diagnostic tool with high sensitivity and specificity for the exact diagnosis of body packing.
放射科医生和其他临床医生面临着越来越多与非法药物相关的医疗状况。我们旨在引起人们对这一日益严重的全球性问题的关注,并强调与身体藏毒相关的诊断和随访的一些要点。我们比较了未增强多排螺旋 CT(MDCT)和腹部 X 射线对检测充满药物的包裹物的诊断性能。
67 名接受 CT 和 X 射线检查的可疑者被纳入研究。所有 MDCT 和 X 射线图像均由两位具有不同腹部成像经验的观察者独立回顾性评估。其中 52 人最终被确定为身体藏毒者。计算了观察者间的一致性、敏感性、特异性、阳性和阴性预测值。
所有身体藏毒者中均发现了两种具有不同特征的包裹物。1 型包裹物(固态药物)见于 41 例患者,2 型包裹物(液态可卡因)见于 11 例患者。所有统计分析均针对任何包裹物的检测。也就是说,整个评估是针对每个患者进行的。MDCT 对 1 型和 2 型包裹物的敏感性/特异性值分别为 100-98%/100-100%和 100-100%/100-100%。此外,X 射线对 1 型和 2 型包裹物的敏感性/特异性值分别为 93-90%/100-91%和 64-45%/73-71%。此外,对任何包裹物的检测的观察者间一致性为优秀(κ=0.96)和良好(κ=0.75),分别用于 MDCT 和 X 射线的解释。
未增强的 MDCT 是一种快速、准确、易于使用的诊断工具,对身体藏毒的准确诊断具有高敏感性和特异性。