新型干扰素 IFN-λ4 失活可能赋予机体对丙型肝炎的保护作用。
Loss of function of the new interferon IFN-λ4 may confer protection from hepatitis C.
机构信息
Institute for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia.
出版信息
Nat Genet. 2013 Feb;45(2):119-20. doi: 10.1038/ng.2537.
DOI:10.1038/ng.2537
PMID:23358218
Abstract
Attempts to elucidate the mechanism underpinning the genetic association between IFNL3, previously called IL28B, and clearance of hepatitis C virus have, by and large, been unsuccessful. A study in this issue suggests that a new gene, IFNL4, may be responsible.
摘要
试图阐明 IFNL3（以前称为 IL28B）与丙型肝炎病毒清除之间遗传关联的机制的努力基本上都没有成功。本期中的一项研究表明，一个新的基因 IFNL4 可能是罪魁祸首。
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