The hedgehog pathway in breast cancer.
作者信息
Ali Sheikh Asim
机构信息
Department of Medical Oncolgy, Temple University Hospital, Philadelphia, Pennsylvania, USA.
出版信息
Chin J Cancer Res. 2012 Dec;24(4):261-2. doi: 10.3978/j.issn.1000-9604.2012.10.02.
Abstract
摘要
相似文献
1
The hedgehog pathway in breast cancer.乳腺癌中的刺猬信号通路。
Chin J Cancer Res. 2012 Dec;24(4):261-2. doi: 10.3978/j.issn.1000-9604.2012.10.02.
2
24-Dehydrocholesterol reductase promotes the growth of breast cancer stem-like cells through the Hedgehog pathway.24-去氢胆固醇还原酶通过 Hedgehog 通路促进乳腺癌干细胞样细胞的生长。
Cancer Sci. 2020 Oct;111(10):3653-3664. doi: 10.1111/cas.14587. Epub 2020 Aug 13.
3
Involvement of hedgehog pathway in early onset, aggressive molecular subtypes and metastatic potential of breast cancer. hedgehog 通路在乳腺癌早期发病、侵袭性分子亚型和转移潜能中的作用。
Cell Commun Signal. 2018 Jan 8;16(1):3. doi: 10.1186/s12964-017-0213-y.
4
Physalin A, 13,14-Seco-16, 24-Cyclo-Steroid, Inhibits Stemness of Breast Cancer Cells by Regulation of Hedgehog Signaling Pathway and Yes-Associated Protein 1 (YAP1).黄甾酮 A，13,14-去氢-16,24-环甾体，通过调控 Hedgehog 信号通路和 Yes 相关蛋白 1（YAP1）抑制乳腺癌细胞干性。
Int J Mol Sci. 2021 Aug 13;22(16):8718. doi: 10.3390/ijms22168718.
5
Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.在良性乳腺组织和乳腺癌中，刺猬信号通路及对环杷明的反应在上皮细胞和基质细胞中存在差异。
Cancer Biol Ther. 2006 Jun;5(6):674-83. doi: 10.4161/cbt.5.6.2906. Epub 2006 Jun 18.
6
Salinomycin exerts anticancer effects on human breast carcinoma MCF-7 cancer stem cells via modulation of Hedgehog signaling.沙利霉素通过调节 Hedgehog 信号通路对人乳腺癌 MCF-7 肿瘤干细胞发挥抗癌作用。
Chem Biol Interact. 2015 Feb 25;228:100-7. doi: 10.1016/j.cbi.2014.12.002. Epub 2014 Dec 8.
7
[Detection of breast cancer stem cells and the expression of key molecules in Hedgehog signaling pathway].[乳腺癌干细胞的检测及Hedgehog信号通路关键分子的表达]
Beijing Da Xue Xue Bao Yi Xue Ban. 2008 Oct 18;40(5):480-5.
8
In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.使用SMO（GDC-0449）或GLI（GANT-61）抑制剂靶向刺猬信号通路/GLI途径对乳腺癌细胞生长的体外和体内抑制作用。
Oncotarget. 2016 Feb 23;7(8):9250-70. doi: 10.18632/oncotarget.7062.
9
Anti-proliferation of breast cancer cells with itraconazole: Hedgehog pathway inhibition induces apoptosis and autophagic cell death.伊曲康唑对乳腺癌细胞的抗增殖作用：抑制刺猬信号通路可诱导细胞凋亡和自噬性细胞死亡。
Cancer Lett. 2017 Jan 28;385:128-136. doi: 10.1016/j.canlet.2016.10.034. Epub 2016 Oct 31.
10
The Hedgehog signalling pathway mediates drug response of MCF-7 mammosphere cells in breast cancer patients.刺猬信号通路介导乳腺癌患者MCF-7乳腺球细胞的药物反应。
Clin Sci (Lond). 2015 Nov;129(9):809-22. doi: 10.1042/CS20140592. Epub 2015 Jul 2.
引用本文的文献
1
Cordycepin Inhibits Growth and Metastasis Formation of MDA-MB-231 Xenografts in Nude Mice by Modulating the Hedgehog Pathway.虫草素通过调节 Hedgehog 通路抑制裸鼠 MDA-MB-231 异种移植瘤的生长和转移形成。
Int J Mol Sci. 2022 Sep 8;23(18):10362. doi: 10.3390/ijms231810362.
2
Hedgehog Autoprocessing: From Structural Mechanisms to Drug Discovery.刺猬蛋白自加工：从结构机制到药物发现
Front Mol Biosci. 2022 May 20;9:900560. doi: 10.3389/fmolb.2022.900560. eCollection 2022.
3
The Hedgehog inhibitor cyclopamine antagonizes chemoresistance of breast cancer cells.刺猬抑制剂环巴胺拮抗乳腺癌细胞的化疗耐药性。
Onco Targets Ther. 2013 Nov 12;6:1643-7. doi: 10.2147/OTT.S51914. eCollection 2013.
4
QM-FISH analysis of the genes involved in the G1/S checkpoint signaling pathway in triple-negative breast cancer.三阴性乳腺癌中G1/S检查点信号通路相关基因的定量荧光原位杂交（QM-FISH）分析
Tumour Biol. 2014 Mar;35(3):1847-54. doi: 10.1007/s13277-013-1246-5. Epub 2013 Oct 5.
本文引用的文献
1
Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway. hedgehog 信号通路在 PI3K/AKT 通路异常激活的他莫昔芬耐药型乳腺癌中是一个新的治疗靶点。
Cancer Res. 2012 Oct 1;72(19):5048-59. doi: 10.1158/0008-5472.CAN-12-1248. Epub 2012 Aug 8.
2
Study on the skip metastasis of axillary lymph nodes in breast cancer and their relation with Gli1 expression.乳腺癌腋窝淋巴结跳跃转移及其与Gli1表达关系的研究
Tumour Biol. 2012 Dec;33(6):1943-50. doi: 10.1007/s13277-012-0455-7. Epub 2012 Jul 14.
3
Efficacy and safety of vismodegib in advanced basal-cell carcinoma.维莫德吉治疗晚期基底细胞癌的疗效和安全性。
N Engl J Med. 2012 Jun 7;366(23):2171-9. doi: 10.1056/NEJMoa1113713.
4
Breast and cervical cancer in 187 countries between 1980 and 2010: a systematic analysis.1980 年至 2010 年 187 个国家的乳腺癌和宫颈癌：系统分析。
Lancet. 2011 Oct 22;378(9801):1461-84. doi: 10.1016/S0140-6736(11)61351-2. Epub 2011 Sep 14.
5
Hedgehog signaling pathway mediates the progression of non-invasive breast cancer to invasive breast cancer.刺猬信号通路介导非浸润性乳腺癌向浸润性乳腺癌的进展。
Cancer Sci. 2011 Feb;102(2):373-81. doi: 10.1111/j.1349-7006.2010.01779.x. Epub 2010 Nov 22.
6
Expression and regulation mechanisms of Sonic Hedgehog in breast cancer.乳腺癌中 Sonic Hedgehog 的表达和调控机制。
Cancer Sci. 2010 Apr;101(4):927-33. doi: 10.1111/j.1349-7006.2010.01495.x. Epub 2010 Jan 15.
7
The Hedgehog pathway is a possible therapeutic target for patients with estrogen receptor-negative breast cancer.刺猬信号通路是雌激素受体阴性乳腺癌患者一个可能的治疗靶点。
Anticancer Res. 2009 Mar;29(3):871-9.
8
Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation.Gli1通过激活基质金属蛋白酶-9促进胰腺癌的侵袭性。
Cancer Sci. 2008 Jul;99(7):1377-84. doi: 10.1111/j.1349-7006.2008.00822.x. Epub 2008 Apr 11.
9
De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis.在胃癌发生的InsGas小鼠模型中，音猬因子信号通路的失调。
Br J Cancer. 2007 Jun 18;96(12):1855-61. doi: 10.1038/sj.bjc.6603782. Epub 2007 May 15.
10
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers.抑制刺猬信号通路可抑制胰腺癌的侵袭和转移：实体癌联合治疗的新范例。
Cancer Res. 2007 Mar 1;67(5):2187-96. doi: 10.1158/0008-5472.CAN-06-3281.
Zotero 插件