Kaboré N F, Poda G E A, Barro M, Cessouma R, Héma A, Ouedraogo A S, Sawadogo A B, Nacro B
Service de maladies infectieuses.
Med Sante Trop. 2012 Oct-Dec;22(4):425-9. doi: 10.1684/mst.2012.0122.
Vaccination against Haemophilus influenzae type b was introduced in Burkina Faso on 1st January 2006. This study thus sought to determine the impact of the first 30 months of vaccination on admissions for Hib meningitis in the department of pediatrics at the Sourô-Sanou University Hospital in Bobo Dioulasso.
Retrospective study of children aged zero to 14 years hospitalized from 1st January 2004 to 30th June 2008 for acute bacterial meningitis (laboratory-confirmed).
During the study period, 416 children were admitted for acute bacterial meningitis. The bacterium isolated was identified in 386 cases and unidentified in 30 cases. Hib meningitis accounted for 42.3 % of the cases of identified bacterial meningitis before the introduction of the vaccine (2004 to 2005). This rate declined to 11.8 % for the first 30 months of vaccination (p < 0.001). No cases of Hib meningitis have been reported in the first half of 2008.
Admissions for Hib meningitis in the Department of Pediatrics have practically disappeared two years after the introduction of the Hib vaccine into Burkina Faso's expanded program on immunization.
2006年1月1日布基纳法索开始引入b型流感嗜血杆菌疫苗接种。因此，本研究旨在确定接种疫苗的头30个月对博博迪乌拉索苏罗 - 萨努大学医院儿科因b型流感嗜血杆菌脑膜炎入院情况的影响。
对2004年1月1日至2008年6月30日因急性细菌性脑膜炎（实验室确诊）住院的0至14岁儿童进行回顾性研究。
在研究期间，416名儿童因急性细菌性脑膜炎入院。386例病例中分离出细菌，30例未分离出。在引入疫苗前（2004年至2005年），b型流感嗜血杆菌脑膜炎占已确诊细菌性脑膜炎病例的42.3%。接种疫苗的头30个月，这一比例降至11.8%（p<0.001）。2008年上半年未报告b型流感嗜血杆菌脑膜炎病例。
在布基纳法索扩大免疫规划引入b型流感嗜血杆菌疫苗两年后，儿科因b型流感嗜血杆菌脑膜炎的入院情况实际上已消失。
