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[青蛙相性肌肉中神经末梢的形成]

[The formation of nerve endings in the phasic muscles of the frog].

作者信息

Dobretsov M G, Zefirov A L, Kurtasanov R S, Khalilov I A, Vinogradova I M

出版信息

Neirofiziologiia. 1990;22(1):99-107.

PMID:2336137
Abstract

Synapses with the complex nerve endings consisting of several terminal branchings of a single axon divided by myelin segments were studied at the cutaneous-pectoris muscles of a frog by histological and electrophysiological methods. It has been revealed that the number of the synapses with complex nerve endings rises during the postnatal development. The relation between the nerve ending complexity, total terminal length and size of the muscle fibres is described. Some of branches in complex nerve endings arise from the Ranvier nodes. They are characterized by a low level of quantal secretion and a peculiar fall of the sodium current along nerve terminals. Mechanisms that induce growth of nerve endings, branching and peculiarities of the transmitter release are discussed. It is supposed that the processes of growth and myelinization of nerve endings take place simultaneously.

摘要

通过组织学和电生理学方法,在青蛙的皮胸肌中研究了与由单个轴突的几个终末分支组成的复杂神经末梢形成的突触,这些分支被髓鞘段分隔。研究发现,在出生后的发育过程中,与复杂神经末梢形成的突触数量会增加。描述了神经末梢复杂性、总终末长度与肌纤维大小之间的关系。复杂神经末梢中的一些分支起源于郎飞结。它们的特点是量子分泌水平低,以及沿神经末梢的钠电流有特殊下降。讨论了诱导神经末梢生长、分支和递质释放特性的机制。据推测,神经末梢的生长和髓鞘形成过程是同时发生的。

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