Germain G
INSERM U166, Maternité Baudelocque, Paris.
Pathol Biol (Paris). 1990 Mar;38(3):159-65.
In the field of reproductive physiology, laboratory primates share large homology with the human species, namely the regulation of the steroid production during gestation, the functional anatomy of the uterus and the lack of any recognized endocrine signal preceding the parturition. Primates are largely used in studies on uterine contractility and on the related controling factors (e.g. steroids, catecholamines, isosanoids...). Other studies attempt to identify the origin of impaired fetal vitality in utero. Primates are also good surrogates to establish safe procedures for antenatal surgery. Constraints in connection with the use of primates are primarely the cost of the animals, their low fertility rate and the fact that only very few species (i.e. macaque and baboon) are available for sophisticated studies.
在生殖生理学领域，实验灵长类动物与人类具有很大的同源性，即在妊娠期类固醇生成的调节、子宫的功能解剖以及分娩前缺乏任何公认的内分泌信号方面。灵长类动物在子宫收缩及相关控制因素（如类固醇、儿茶酚胺、类异戊二烯等）的研究中被大量使用。其他研究试图确定子宫内胎儿活力受损的根源。灵长类动物也是建立产前手术安全程序的良好替代对象。与使用灵长类动物相关的限制主要是动物成本、低生育率以及仅有极少数物种（即猕猴和狒狒）可用于复杂研究这一事实。
