Thawley Vincent J, Suran Jantra N, Boller Elise M
Section of Critical Care, Department of Clinical Studies – Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
J Vet Emerg Crit Care (San Antonio). 2013 May-Jun;23(3):335-9. doi: 10.1111/vec.12014. Epub 2013 Jan 30.
To describe the clinical course and successful management of a dog suspected to have central nervous system (CNS) Cuterebra larval migration and concurrent protein-losing nephropathy (PLN).
A 1-year-old castrated male mixed breed dog was diagnosed with presumptive CNS cuterebriasis based on history, progressively deteriorating mentation, seizures, and magnetic resonance images showing a tubular lesion consistent with a migrating Cuterebra tract. Additionally, serum biochemistry and urine analyses revealed the development of a severe PLN. Surgical removal of the Cuterebra was attempted unsuccessfully, and subsequently, the dog was treated with ivermectin, antihistamines, anticonvulsants, and a tapering dose of glucocorticoids. Over several weeks the dog's neurologic status improved and the PLN resolved completely.
This case describes successful management of presumptive CNS cuterebriasis in a dog. It is also, to our knowledge, the first report of PLN associated with cuterebriasis in the veterinary literature.
描述一只疑似患有中枢神经系统（CNS）皮肤蝇蛆移行症并并发蛋白质丢失性肾病（PLN）的犬的临床病程及成功治疗情况。
一只1岁去势雄性混种犬，根据病史、逐渐恶化的精神状态、癫痫发作以及磁共振成像显示与移行性皮肤蝇通道一致的管状病变，被诊断为疑似中枢神经系统皮肤蝇蛆病。此外，血清生化和尿液分析显示出现了严重的蛋白质丢失性肾病。尝试手术摘除皮肤蝇未成功，随后该犬接受了伊维菌素、抗组胺药、抗惊厥药以及逐渐减量的糖皮质激素治疗。数周后，该犬的神经状态改善，蛋白质丢失性肾病完全缓解。
本病例描述了犬疑似中枢神经系统皮肤蝇蛆病的成功治疗情况。据我们所知，这也是兽医文献中首例与皮肤蝇蛆病相关的蛋白质丢失性肾病报告。
