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影像诊断——一只幼犬中表现为轴内脑肿块的恶性外周神经鞘瘤。

Imaging diagnosis-malignant peripheral nerve sheath tumor presenting as an intra-axial brain mass in a young dog.

作者信息

Shihab Nadia, Summers Brian A, Benigni Livia, McEvoy Andrew W, Volk Holger A

机构信息

Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire, AL9 7TA, UK.

出版信息

Vet Radiol Ultrasound. 2013 May-Jun;54(3):278-82. doi: 10.1111/vru.12011. Epub 2013 Jan 30.

DOI:10.1111/vru.12011
PMID:23363000
Abstract

A 3-year-old Labrador retriever was presented with acute onset seizures. Magnetic resonance imaging demonstrated an intra-axial mass affecting the right temporal lobe of the brain. Surgical resection and histopathological findings were most consistent with a malignant peripheral nerve sheath tumor. After initial recovery, deterioration 3 months post surgery prompted euthanasia. Post-mortem revealed a mass protruding from the ventral surface of the temporal lobe, encroaching upon the optic chiasm and invading the brain. Histopathology findings were again consistent with malignant peripheral nerve sheath tumor. Although rare, this tumor should be included as a possible differential diagnosis for intra-axial brain masses in dogs.

摘要

一只3岁的拉布拉多猎犬出现急性发作性癫痫。磁共振成像显示脑内轴位肿块,影响右侧颞叶。手术切除及组织病理学检查结果最符合恶性外周神经鞘瘤。术后初期恢复后,术后3个月病情恶化,最终实施安乐死。尸检发现颞叶腹面有一肿块突出,侵犯视交叉并侵入脑部。组织病理学检查结果再次符合恶性外周神经鞘瘤。尽管这种肿瘤罕见,但在犬脑内轴位肿块的鉴别诊断中应将其列为可能的鉴别诊断之一。

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Case report: Presumptive subcutaneous malignant peripheral nerve sheath tumor with intracranial invasion and osteolysis in the posterior fossa of a dog.病例报告:一只犬后颅窝出现疑似伴有颅内侵犯和骨质溶解的皮下恶性外周神经鞘瘤。
Front Vet Sci. 2022 Nov 8;9:977099. doi: 10.3389/fvets.2022.977099. eCollection 2022.
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Colonic malignant peripheral nerve sheath tumour in a cat.一只猫的结肠恶性外周神经鞘瘤。
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