非ST段抬高型急性冠状动脉综合征患者的主动脉结钙化与冠状动脉病变复杂性
Aortic knob calcification and coronary artery lesion complexity in non-ST-segment elevation acute coronary syndrome patients.
作者信息
Korkmaz Levent, Adar Adem, Ata Korkmaz Ayça, Erkan Hakan, Ağaç Mustafa Tarık, Acar Zeydin, Akyüz Ali Rıza, Bektaş Hüseyin, Celik Sükrü
机构信息
Ahi Evren Thorasic and Cardiovascular Surgery Training and Research Hospital, Trabzon, Turkey.
出版信息
Turk Kardiyol Dern Ars. 2012 Oct;40(7):606-11. doi: 10.5543/tkda.2012.38963.
OBJECTIVES
Coronary artery lesion complexity is important for risk stratification of acute coronary syndrome (ACS) patients undergoing cardiac catheterization. SYNTAX score is a pure angiographic measure of anatomic coronary complexity. Chest radiography is a routine examination for evaluating patients with chest pain. There have been no studies to date exploring the relation between aortic knob calcification (AKC) and coronary lesion complexity assessed by SYNTAX score.
STUDY DESIGN
135 consecutive patients with first time diagnosis of non-ST segment elevation ACS were enrolled. SYNTAX score was calculated by dedicated computer software. Aortic calcification was assessed visually.
RESULTS
Patients with AKC had higher SYNTAX score compared to those without AKC (16±6 vs. 11±7, p=0.019). Also, patients with AKC had higher TIMI risk score and were more elderly. Linear regression analysis demonstrated AKC (95% confidence interval [CI] 1.7-6.9, p=0.002), diabetes (95% CI, 1.1-5.7, p=0.005), and smoking (95% CI, 1.2-13.5, p=0.004) as independent determinants of SYNTAX score.
CONCLUSION
Aortic calcification detected on chest X-ray is an independent predictor of complex coronary artery lesions in patients with ACS.
目的
冠状动脉病变复杂性对于接受心脏导管插入术的急性冠状动脉综合征（ACS）患者的风险分层很重要。SYNTAX评分是一种纯粹基于血管造影的冠状动脉解剖复杂性测量方法。胸部X线摄影是评估胸痛患者的常规检查。迄今为止，尚无研究探讨主动脉结钙化（AKC）与通过SYNTAX评分评估的冠状动脉病变复杂性之间的关系。
研究设计
连续纳入135例首次诊断为非ST段抬高型ACS的患者。通过专用计算机软件计算SYNTAX评分。通过视觉评估主动脉钙化情况。
结果
与无AKC的患者相比，有AKC的患者SYNTAX评分更高（16±6对11±7，p = 0.019）。此外，有AKC的患者TIMI风险评分更高，且年龄更大。线性回归分析表明，AKC（95%置信区间[CI] 1.7 - 6.9，p = 0.002）﹑糖尿病（95% CI，1.1 - 5.7，p = 0.005）和吸烟（95% CI，1.2 - 13.5，p = 0.004）是SYNTAX评分的独立决定因素。
结论
胸部X线检查发现的主动脉钙化是ACS患者复杂冠状动脉病变的独立预测因素。
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