Medical Research Council/Uganda Virus Research Institute (MRC/UVRI), Uganda Research Unit on AIDS, Entebbe, Uganda.
Int J Epidemiol. 2013 Feb;42(1):129-41. doi: 10.1093/ije/dys234. Epub 2013 Jan 30.
The General Population Cohort (GPC) was set up in 1989 to examine trends in HIV prevalence and incidence, and their determinants in rural south-western Uganda. Recently, the research questions have included the epidemiology and genetics of communicable and non-communicable diseases (NCDs) to address the limited data on the burden and risk factors for NCDs in sub-Saharan Africa. The cohort comprises all residents (52% aged ≥13years, men and women in equal proportions) within one-half of a rural sub-county, residing in scattered houses, and largely farmers of three major ethnic groups. Data collected through annual surveys include; mapping for spatial analysis and participant location; census for individual socio-demographic and household socioeconomic status assessment; and a medical survey for health, lifestyle and biophysical and blood measurements to ascertain disease outcomes and risk factors for selected participants. This cohort offers a rich platform to investigate the interplay between communicable diseases and NCDs. There is robust infrastructure for data management, sample processing and storage, and diverse expertise in epidemiology, social and basic sciences. For any data access enquiries you may contact the director, MRC/UVRI, Uganda Research Unit on AIDS by email to mrc@mrcuganda.org or the corresponding author.
一般人群队列（GPC）于 1989 年成立，旨在研究乌干达西南部农村地区 HIV 流行率和发病率的趋势及其决定因素。最近，研究问题包括传染病和非传染性疾病（NCDs）的流行病学和遗传学，以解决撒哈拉以南非洲地区 NCDs 负担和风险因素数据有限的问题。该队列包括居住在一个农村半县范围内的所有居民（52%年龄≥13 岁，男女比例相等），他们居住在分散的房屋中，主要是三个主要族群的农民。通过年度调查收集的数据包括：进行空间分析和参与者位置的绘图；人口普查以评估个人社会人口统计学和家庭社会经济地位；以及医疗调查以了解健康、生活方式和生物物理以及血液测量结果，以确定选定参与者的疾病结局和风险因素。该队列为研究传染病和非传染性疾病之间的相互作用提供了丰富的平台。该队列拥有强大的数据管理、样本处理和存储基础设施，以及在流行病学、社会和基础科学方面的多样化专业知识。如需任何数据访问查询，您可以通过电子邮件联系 MRC/UVRI，乌干达艾滋病研究单位主任，mrc@mrcuganda.org，或联系相应的作者。
