Ikeda Hirokuni, Takeo Masahiko, Kayata Hiroyuki, Mikami Ryuuichi, Nakamoto Yoshihiko, Yamamoto Mistuo
Kobe City Hospital Organization Kobe City Center West Hospital, Kobe, Hyogo, Japan.
Ann Thorac Cardiovasc Surg. 2014;20 Suppl:521-4. doi: 10.5761/atcs.cr.12.02069. Epub 2013 Jan 31.
A 37-year-old woman noticed a right anterior chest mass and pain. The mass had been rapidly growing and she visited our hospital. The mass was hard and 8 × 7 cm in size. It was detected in the upper inner quadrant of her anterior chest wall. A computed tomography (CT) examination and magnetic resonance imaging (MRI) of the chest revealed a large heterogeneously enhanced mass arising from the right chest wall with lytic destruction of the rib and coarse calcification. An image diagnosis of osteogenic sarcoma originating from a rib was made. She underwent surgical excision of the tumor and chest wall reconstruction. Microscopic examination of the resected tumor showed multiple neoplastic cells accompanied by osteoid formation within the tumor. The tumor was diagnosed as high-grade malignant osteosarcoma of the rib. Primary osteosarcoma commonly originates in the long bone in children and adolescents, but it occurs very rarely in the ribs in adults. Surgical resection plays an important role in the treatment for this disease. We report a case of primary osteosarcoma that originated in the rib of a young woman and was treated successfully by surgery.
一名37岁女性发现右前胸有肿块及疼痛。该肿块生长迅速，遂前来我院就诊。肿块质地坚硬，大小为8×7厘米，位于前胸壁的上内侧象限。胸部计算机断层扫描（CT）检查及磁共振成像（MRI）显示，右胸壁有一个巨大的不均匀强化肿块，伴有肋骨溶骨性破坏及粗大钙化。影像诊断为起源于肋骨的骨肉瘤。她接受了肿瘤切除及胸壁重建手术。对切除肿瘤的显微镜检查显示，肿瘤内有多个肿瘤细胞并伴有类骨质形成。该肿瘤被诊断为肋骨高级别恶性骨肉瘤。原发性骨肉瘤通常起源于儿童和青少年的长骨，但在成人肋骨中极为罕见。手术切除在该病的治疗中起着重要作用。我们报告一例起源于年轻女性肋骨的原发性骨肉瘤，并通过手术成功治疗的病例。
