Barsky A J, Wyshak G, Klerman G L, Latham K S
Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston.
Soc Psychiatry Psychiatr Epidemiol. 1990 Mar;25(2):89-94. doi: 10.1007/BF00794988.
Forty-one DSM-III-R hypochondriacs were obtained by screening consecutive visitors to a general medical clinic and compared with 76 patients randomly chosen from the same setting. They completed a research battery consisting of a structured diagnostic interview (DIS) and self-report questionnaires to measure hypochondriacal symptoms and functional impairment. The criterion standard for diagnosing hypochondriasis was a structured interview of demonstrated reliability and validity. The six-month prevalence of DSM-III-R hypochondriasis was estimated to be between 4.2% and 6.3% of consecutive attenders who met the inclusion criterion of having visited the same physician before. This rate was somewhat lower than that found for generalized anxiety disorder and comparable to that of alcohol abuse. The hypochondriacal patients did not differ significantly from the comparison random sample in sociodemographic risk factors except that they were significantly more likely to be Black. Hypochondriacal symptomatology was similar in males and females; and in those over 65 and those under 65. Over a three-week interval, hypochondriacal symptoms remained stable, and hypochondriacal patients had significantly higher levels of long-term disability than did the comparison patients.
通过对一家普通内科诊所的连续就诊者进行筛查,选取了41名符合《精神疾病诊断与统计手册》第三版修订版(DSM-III-R)中疑病症诊断标准的患者,并与从同一诊所随机选取的76名患者进行比较。他们完成了一套研究测试,包括结构化诊断访谈(DIS)和自我报告问卷,以测量疑病症症状和功能损害。诊断疑病症的标准是经过验证具有可靠性和有效性的结构化访谈。DSM-III-R疑病症的六个月患病率估计在符合纳入标准(即在该诊所之前曾就诊于同一位医生)的连续就诊者的4.2%至6.3%之间。这一患病率略低于广泛性焦虑症的患病率,与酒精滥用的患病率相当。除了黑人患者的比例显著更高外,疑病症患者与随机抽取的对照组在社会人口统计学风险因素方面没有显著差异。男性和女性、65岁以上和65岁以下人群的疑病症症状相似。在三周的时间间隔内,疑病症症状保持稳定,疑病症患者的长期残疾水平显著高于对照组患者。