Lindholm J, Kehlet H, Blichert-Toft M, Dinesen B, Riishede J
J Clin Endocrinol Metab. 1978 Aug;47(2):272-4. doi: 10.1210/jcem-47-2-272.
An insulin hypoglycemia test and a 30-min ACTH test were performed in 90 patients with proved or suspected hypothalamic-pituitary-adrenal hypofunction and in 10 normal subjects. The peak plasma cortisol concentration during hypoglycemia and the cortisol concentration at 30 min after injection of 250 micrograms corticotropin 1-24 were compared. A very close correlation (r = 0.92) was found between the the two concentrations, with no major discrepancy in any case. It is concluded that the short ACTH test accurately reflects the integrated hypothalamic-pituitary-adrenal function, as assessed by the insulin hypoglycemia test.
对90例已证实或疑似下丘脑 - 垂体 - 肾上腺功能减退的患者及10名正常受试者进行了胰岛素低血糖试验和30分钟促肾上腺皮质激素（ACTH）试验。比较了低血糖期间血浆皮质醇浓度峰值与注射250微克促肾上腺皮质激素1 - 24后30分钟时的皮质醇浓度。发现这两种浓度之间存在非常密切的相关性（r = 0.92），在任何情况下均无重大差异。结论是，如通过胰岛素低血糖试验所评估的，短时间ACTH试验能准确反映下丘脑 - 垂体 - 肾上腺的整体功能。
