使用数字电子设计流程来创建一个基因设计自动化工具。
Using digital electronic design flow to create a Genetic Design Automation tool.
作者信息
Gendrault Y, Madec M, Wlotzko V, Andraud M, Lallement C, Haiech J
机构信息
Institut d’Electronique du Solide et des Systèmes (InESS Institute of Electronics for Solids and Systems), Université de Strasbourg(Unistra) and the Centre National de Recherches Scientifiques (CNRS),UMR7163, Strasbourg, France.
出版信息
Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:5530-3. doi: 10.1109/EMBC.2012.6347247.
Synthetic bio-systems become increasingly more complex and their development is lengthy and expensive. In the same way, in microelectronics, the design process of very complex circuits has benefited from many years of experience. It is now partly automated through Electronic Design Automation tools. Both areas present analogies that can be used to create a Genetic Design Automation tool inspired from EDA tools used in digital electronics. This tool would allow moving away from a totally manual design of bio-systems to assisted conception. This ambitious project is presented in this paper, with a deep focus on the tool that automatically generates models of bio-systems directly usable in electronic simulators.
合成生物系统变得越来越复杂，其开发过程漫长且成本高昂。同样，在微电子领域，非常复杂电路的设计过程受益于多年的经验。现在，它通过电子设计自动化工具实现了部分自动化。这两个领域存在相似之处，可用于创建一种受数字电子学中使用的EDA工具启发的基因设计自动化工具。该工具将使生物系统的设计从完全手动设计转向辅助概念设计。本文介绍了这个雄心勃勃的项目，重点深入探讨了能直接生成可在电子模拟器中使用的生物系统模型的工具。
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