Qassem M, Kyriacou P A
City University London, Northampton square, London.
Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:6044-7. doi: 10.1109/EMBC.2012.6347372.
The application of Near Infrared Spectroscopy(NIRS) for measuring skin water content has long been established, and has gained w ide interest as a precise, safe, fast and noninvasive technique for determining skin hydration.This paper reports near infrared spectrophotometric measurements using a highly sophisticated spectrophotometer in the region of 1000-2500 nm to study the water uptake and dehydration properties of skin in vitro using samples of porcine skin. Initial results of pure liquid water and skin samples have clearly displayed the prominent bands associated with water content, and desorption tests have been able to verify changes in these bands associated with water content, although a clear correlation between the rates of weight loss and absorbance loss at various hydration periods has not yet been established. These preliminary results are expected to further explain the relationship between water and skin, and its role within, in hope to aid the future development of a portable instrument based on near infrared spectroscopy that would be capable of directly measuring skin hydration and/or water content in a fast and noninvasive manner.
近红外光谱法（NIRS）用于测量皮肤含水量早已得到应用，并且作为一种精确、安全、快速且无创的测定皮肤水合作用的技术受到了广泛关注。本文报道了使用高度精密的分光光度计在1000 - 2500 nm区域进行近红外分光光度测量，以利用猪皮样本在体外研究皮肤的吸水和脱水特性。纯水和皮肤样本的初步结果清楚地显示了与含水量相关的显著谱带，并且解吸试验已经能够验证这些与含水量相关的谱带的变化，尽管尚未建立不同水合阶段重量损失率和吸光度损失率之间的明确相关性。这些初步结果有望进一步解释水与皮肤之间的关系及其在皮肤中的作用，以期有助于未来基于近红外光谱技术开发一种便携式仪器，该仪器能够以快速且无创的方式直接测量皮肤水合作用和/或含水量。
