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羟考酮+纳洛酮：改为选用吗啡及最佳的缓泻疗法。

Oxycodone + naloxone: choose morphine and optimal laxative therapy instead.

出版信息

Prescrire Int. 2013 Jan;22(134):10-1.

PMID:23367675
Abstract

At high doses of oxycodone, the fixed-dose combination of oxycodone plus naloxone complicates therapeutic management and will likely have lower analgesic efficacy.

摘要

在高剂量羟考酮的情况下，羟考酮与纳洛酮的固定剂量组合会使治疗管理复杂化，并且镇痛效果可能会降低。

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