Department of Psychiatry, Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia.
Pain Med. 2013 Mar;14(3):336-44. doi: 10.1111/pme.12034. Epub 2013 Jan 31.
Patients with pain 3 years after injury are at risk of lifetime pain. It is not known if the predictors of chronic pain at 3 years are the same as those for earlier time points or whether other factors become important. Clarifying these factors will aid our understanding of the development of long-term pain and further inform the development of models for screening and early intervention for pain in the aftermath of injury.
Patients admitted to two trauma centers underwent a comprehensive physical and psychological assessment of known and potential risk factors for chronic pain during their index admission. Three years after injury, these patients were assessed for the presence of chronic pain (score was ≥5 on an 11-point numerical rating scale during the last episode of pain, and present in the last month and at least two times in the past week) and pain-related disability. Logistic regression was used to identify independent risk factors for the presence of chronic pain and disability.
Two hundred and twenty patients (75.9% of the original cohort) were assessed at 3 years. Of these, 146 (66.7%) reported some pain and 52 (23.7%) reported chronic pain. Factors (present at the time of injury) that predicted chronic pain were lower socioeconomic status, pain severity, and injury severity. The predictive power of these combined factors was modest.
Three years after serious injury, almost a quarter of patients report chronic pain, and more than a third report at least moderate pain-related disability. The predicative power of measures taken in the acute setting is not enough to support discharge screening alone as a method of triaging high-risk patients to early intervention.
受伤 3 年后出现疼痛的患者有终生疼痛的风险。目前尚不清楚 3 年后慢性疼痛的预测因素是否与早期时间点的预测因素相同,或者是否有其他因素变得重要。明确这些因素将有助于我们了解长期疼痛的发展,并进一步为受伤后疼痛的筛查和早期干预模型的开发提供信息。
入住两家创伤中心的患者在其入院期间接受了全面的身体和心理评估,以了解慢性疼痛的已知和潜在风险因素。受伤 3 年后,对这些患者进行慢性疼痛(在最后一次疼痛发作期间数字评分量表上得分为≥5,并且在过去一个月内和过去一周内至少两次出现)和疼痛相关残疾的评估。使用逻辑回归来确定慢性疼痛和残疾存在的独立风险因素。
220 名患者(原始队列的 75.9%)在 3 年后接受了评估。其中,146 名(66.7%)报告有一定程度的疼痛,52 名(23.7%)报告有慢性疼痛。预测慢性疼痛的因素(在受伤时存在)包括较低的社会经济地位、疼痛严重程度和损伤严重程度。这些综合因素的预测能力适中。
在严重受伤 3 年后,近四分之一的患者报告有慢性疼痛,超过三分之一的患者报告有至少中度的疼痛相关残疾。在急性期采取的措施的预测能力不足以支持单独作为高危患者早期干预的分诊方法的出院筛查。