Gastroenterology Department, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
Dig Endosc. 2013 Sep;25(5):502-7. doi: 10.1111/den.12021. Epub 2012 Dec 26.
Our aim was to study the efficacy and safety of different types of intragastric balloon in morbidly obese patients.
From 2005 to 2011, intragastric balloons were inserted endoscopically into 32 patients. Intragastric balloons were used in morbidly obese (body mass index [BMI] ≥ 35 kg/m(2) ) individuals who were non-responsive to 6-month medical therapy and diet. Balloons were endoscopically removed after 6 months.
Thirty-six balloons were inserted in a total of 32 patients. Mean age of the patients was 37.28 ± 12.08 (17-64) years and mean height was 169.81 ± 8.17 (150-185) cm. Initial mean weight was 128.87 ± 23.31 kg and BMI was 45.26 ± 8.48 kg/m(2) . At month 6, mean bodyweight was 116.93 ± 23.18 and BMI was 40.96 ± 7.96 kg/m(2) (P < 0.001, P < 0.001, respectively). At the end of 6 months, while the excessweight loss (EWL) median was 13.0 kg, [interquartile range IQR: 5.0-16.0] and percent EWL median was 21.92, [IQR: 12.72-28.49] in the Heliosphere BAG patients, the EWL median was 19.0 kg, [IQR: 14.47-26.72] and the percent EWL median was 38.26, [IQR: 19.73-47.79] in the BioEnterics Intragastric Balloon patients (P = 0.006, P = 0.010, respectively for EWL median and percent EWL median). One patient died (3.1%) of cardiac arrest due to aspiration at day 13 after BIB placement.
Although not without risk, intragastric balloon placement is an effective method for weight loss. BioEnterics Intragastric Balloon is more effective in helping weight loss than the Heliosphere BAG balloon.
我们的目的是研究不同类型的胃内球囊在病态肥胖患者中的疗效和安全性。
2005 年至 2011 年，32 例患者经内镜插入胃内球囊。胃内球囊用于对 6 个月的药物治疗和饮食无反应的病态肥胖（体重指数[BMI]≥35kg/m²）个体。6 个月后经内镜取出球囊。
共 32 例患者共插入 36 个球囊。患者的平均年龄为 37.28±12.08（17-64）岁，平均身高为 169.81±8.17（150-185）cm。初始平均体重为 128.87±23.31kg，BMI 为 45.26±8.48kg/m²。6 个月时，平均体重为 116.93±23.18kg，BMI 为 40.96±7.96kg/m²（P<0.001，P<0.001）。6 个月结束时，Heliosphere BAG 组的超重减轻量（EWL）中位数为 13.0kg，[四分位距 IQR：5.0-16.0]，EWL 百分比中位数为 21.92%，[IQR：12.72-28.49]，而 BioEnterics Intragastric Balloon 组的 EWL 中位数为 19.0kg，[IQR：14.47-26.72]，EWL 百分比中位数为 38.26%，[IQR：19.73-47.79]（P=0.006，P=0.010，分别用于 EWL 中位数和 EWL 百分比中位数）。1 例患者（3.1%）在 BIB 放置后第 13 天因吸入性心脏骤停死亡。
尽管存在风险，但胃内球囊放置是一种有效的减肥方法。BioEnterics Intragastric Balloon 比 Heliosphere BAG 球囊更有效地帮助减肥。
