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[儿童双侧肾母细胞瘤]

[Bilateral nephroblastoma in children].

作者信息

Koczyński A

出版信息

Probl Med Wieku Rozwoj. 1979;9:340-7.

PMID:233708
Abstract

The rarity of such form of nephroblastoma containing about 4% among embryonal renal tumors in this paper, was the subject of special attention. The necessity of preoperative differential diagnosis particularly in cases of congenital multicystic kidney, congenital hydronephrosis and retroperitoneal sympathetic neoplasms was stressed. Radiological investigation facilitate distinguishing of the three pathological forms. A multicystic degeneration of kidney is usually bilateral and it includes both the medulla and the renal cortex. The cystic patterns nearly equal in size are multiple and minute. In the bilateral Wilms' tumour besides the kidney enlargement there are deformations such as hydrocalyx , hydronephrosis or modeling signs. In case of congenital hydronephrosis the kidney keeps the same size and produces the thinner cortex zone. The neoplasms of the sympathetic nerve origin produce first the displacement of kidney and then the deformation of pelvico -calyceal system with modeling signs and sometimes with hydronephrosis. In the above mentioned entities, late urographical pictures are of great significance. The angiographic investigations of kidney play a very important part in the differential diagnosis and planning of operative procedures. The nephrographic phase of angiography shows the quantity and location of active renal parenchyma. A renal arteriography is also important in the evaluation of the applied therapy, particularly in case of multistage therapeutic procedures.

摘要

本文中这种形式的肾母细胞瘤在胚胎性肾肿瘤中较为罕见,约占4%,是特别关注的对象。强调了术前鉴别诊断的必要性,尤其是在先天性多囊肾、先天性肾积水和腹膜后交感神经肿瘤的病例中。影像学检查有助于区分这三种病理形式。肾的多囊性退变通常是双侧的,包括髓质和肾皮质。大小几乎相等的囊性结构是多发且微小的。在双侧威尔姆斯瘤中,除了肾脏增大外,还有诸如肾盂积水、肾积水或塑形征等变形。在先天性肾积水的情况下,肾脏大小保持不变,皮质区变薄。交感神经起源的肿瘤首先导致肾脏移位,然后肾盂肾盏系统变形,伴有塑形征,有时伴有肾积水。在上述病变中,晚期尿路造影照片具有重要意义。肾脏血管造影检查在鉴别诊断和手术方案规划中起着非常重要的作用。血管造影的肾实质造影期显示活跃肾实质的数量和位置。肾动脉造影在评估所应用的治疗方法时也很重要,特别是在多阶段治疗过程中。

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