Department of Anesthesiology and Pain Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Korean J Anesthesiol. 2013 Jan;64(1):40-6. doi: 10.4097/kjae.2013.64.1.40. Epub 2013 Jan 21.
The purpose of this study was to determine the prevalence of non-neurologic complications following surgery for scoliosis and to identify factors that can increase this risk.
The demographic data, medical and surgical histories, and prevalence of non-neurologic complications were reviewed in a retrospective cohort of 602 patients, who had undergone corrective surgery for scoliosis between January 2001 and June 2011.
There were 450 patients under 20 years old (U20) and 152 of patients above 20 years old (A20) enrolled in this study. Forty-nine patients in U20 (10.9%) and 18 patients in A20 (11.8%) had post-operative complications. Respiratory complications were most common in U20 (4%) and gastrointestinal complications were most common in A20 (7%). There was no significant difference between the 2 groups in the prevalence of complications. Logistic regression revealed that factors that correlated with an increased odds for complications were Cobb angle (P = 0.001/P = 0.013, respectively), length of operation time (P = 0.003/P = 0.006, respectively), duration of anesthesia (P < 0.001/P = 0.005, respectively) and transfusion (P = 0.003/P = 0.015, respectively) in U20 and A20. Also, comorbidities (P = 0.021) in U20, and decreased body mass index (P = 0.030), pre-operative forced vital capacity (P = 0.001), forced expired volume in 1s (P = 0.001), increased numbers of vertebrae fused (P = 0.004), blood loss (P = 0.001) in A20 were associated with increased odds for complications.
There was no difference in the prevalence of complication in scoliosis patients by age. The prevalence of complication was dependent on Cobb angle, length of operation time, duration of anesthesia and transfusion of PRBC. Deterioration of preoperative pulmonary function significantly increased risk of post-operative complications in adult patients.
本研究旨在确定脊柱侧弯手术后非神经系统并发症的发生率,并确定可能增加这种风险的因素。
回顾性分析了 2001 年 1 月至 2011 年 6 月期间接受脊柱矫正手术的 602 例患者的人口统计学数据、医疗和手术史以及非神经系统并发症的发生率。
本研究共纳入 450 例 20 岁以下(U20)和 152 例 20 岁以上(A20)患者。U20 中有 49 例(10.9%)和 A20 中有 18 例(11.8%)患者术后发生并发症。U20 中最常见的并发症是呼吸系统并发症(4%),A20 中最常见的并发症是胃肠道并发症(7%)。两组并发症发生率无显著差异。Logistic 回归显示,与并发症发生率增加相关的因素包括 Cobb 角(P = 0.001/P = 0.013)、手术时间(P = 0.003/P = 0.006)、麻醉时间(P < 0.001/P = 0.005)和输血(P = 0.003/P = 0.015)。U20 中还包括合并症(P = 0.021),A20 中包括体重指数降低(P = 0.030)、术前用力肺活量(P = 0.001)、1 秒用力呼气量(P = 0.001)、融合椎骨数量增加(P = 0.004)和失血量(P = 0.001)。
年龄对脊柱侧弯患者并发症的发生率无影响。并发症的发生率取决于 Cobb 角、手术时间、麻醉时间和 PRBC 输血。成年患者术前肺功能恶化显著增加术后并发症的风险。