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后路内固定融合术治疗非退行性脊柱侧凸术后肺部并发症的危险因素。

Risk factors for postoperative pulmonary complications in the treatment of non-degenerative scoliosis by posterior instrumentation and fusion.

机构信息

Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, GongTiNanLu 8#, Chaoyang District, Beijing, 100020, China.

出版信息

Eur Spine J. 2019 Jun;28(6):1356-1362. doi: 10.1007/s00586-019-05968-5. Epub 2019 Apr 8.

DOI:10.1007/s00586-019-05968-5
PMID:30963290
Abstract

PURPOSE

The aim of this study was to evaluate the prevalence and risk factors for postoperative pulmonary complications (PPC) after posterior instrumentation and fusion (PIF) in patients with non-degenerative scoliosis.

METHODS

We retrospectively evaluated 703 patients (224 males, 479 females) diagnosed with non-degenerative scoliosis who underwent PIF in our center from January 2010 to January 2018. Preoperative, perioperative, demographic data, surgical methods and radiographic parameters were extracted and analyzed to identify risk factors for PPC.

RESULTS

The mean age of the patients was 20.8 ± 9.0 years with the following diagnoses: congenital scoliosis (287/703, 40.8%), idiopathic scoliosis (281/703, 40.0%), neuromuscular scoliosis (103/703, 14.7%) and syndromic scoliosis (32/703, 4.5%). PPC manifested in 82 patients (11.7%) including pleural effusion (39/82, 47.6%), pneumonia (33/82, 40.2%), pneumothorax (3/82, 3.7%), respiratory failure (3/82, 3.7%), hemothorax (2/82, 2.4%), pulmonary edema (1/82, 1.2%) and pulmonary embolism (1/82, 1.2%). Multifactorial regression analysis confirmed that revision surgery [odds ratio (OR) = 2.320, P = 0.030], preoperative respiratory disease (OR = 14.286, P < 0.001), preoperative Cobb angle of main curve > 75° (OR = 1.701, P = 0.046) and thoracoplasty (OR = 4.098 P < 0.001) were risk factors for PPC after PIF in patients with non-degenerative scoliosis.

CONCLUSIONS

A prevalence of 11.7% PPC was observed after PIF. Risk factors were preoperative Cobb angle of main curve > 75°, preoperative respiratory disease, revision surgery and thoracoplasty. Surgeons should recognize and pay attention to these risk factors and take appropriate preventive measures to prevent severe pulmonary complications. These slides can be retrieved under Electronic Supplementary Material.

摘要

目的

本研究旨在评估非退行性脊柱侧凸患者后路内固定融合术后肺部并发症(PPC)的发生率及相关危险因素。

方法

回顾性分析 2010 年 1 月至 2018 年 1 月在我院行后路内固定融合术的 703 例非退行性脊柱侧凸患者(男 224 例,女 479 例)。收集患者术前、围手术期、人口统计学资料、手术方法及影像学参数,分析 PPC 的危险因素。

结果

患者平均年龄为 20.8±9.0 岁,诊断包括先天性脊柱侧凸(287/703,40.8%)、特发性脊柱侧凸(281/703,40.0%)、神经肌肉型脊柱侧凸(103/703,14.7%)和综合征型脊柱侧凸(32/703,4.5%)。82 例(11.7%)患者发生 PPC,表现为胸腔积液(39/82,47.6%)、肺炎(33/82,40.2%)、气胸(3/82,3.7%)、呼吸衰竭(3/82,3.7%)、血胸(2/82,2.4%)、肺水肿(1/82,1.2%)和肺栓塞(1/82,1.2%)。多因素回归分析证实,翻修手术(OR=2.320,P=0.030)、术前呼吸系统疾病(OR=14.286,P<0.001)、主弯术前 Cobb 角>75°(OR=1.701,P=0.046)和胸廓成形术(OR=4.098,P<0.001)是非退行性脊柱侧凸患者后路内固定融合术后 PPC 的危险因素。

结论

后路内固定融合术后 PPC 的发生率为 11.7%。危险因素包括主弯术前 Cobb 角>75°、术前呼吸系统疾病、翻修手术和胸廓成形术。外科医生应认识到这些危险因素并加以重视,并采取适当的预防措施,以防止严重的肺部并发症。这些幻灯片可在电子补充材料中检索。

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