Mahar Pir Salim, Manzar Nabeel
Section of Ophthalmology, Department of Surgery, The Aga Khan University Hospital, Karachi.
J Coll Physicians Surg Pak. 2013 Feb;23(2):120-3.
To establish the usefulness of grading system based on the size and extent of corneal involvement in predicting recurrence in patients undergoing primary pterygium excision with intraoperative use of adjunctive topical Mitomycin-C (MMC).
A case series.
Section of Ophthalmology, the Aga Khan University Hospital, Karachi, from 2005 till 2010.
One hundred and twenty male patients (120 eyes) underwent surgical removal of pterygium using bare sclera method with MMC in concentration of 0.2 mg/ml (0.02%) with exposure time of 3 minutes. Classification of subjects was done according to the grading of pterygium. Patients were followed at 3 months interval for a minimum period of 1 year to record any recurrence.
The pterygium recurrence rate was 6.7% at a follow-up of 1 year. There was no significant association of pterygium recurrence with younger age (p = 0.14). A higher level of corneal involvement by the pterygium at presentation correlated significantly with the recurrence (p = 0.01).
These results suggest that a higher grade of pterygium at presentation in patients leads to increased rate of recurrence after surgical excision. Hence, early excision of pterygium is recommended to decrease its recurrence rate.
建立一种基于角膜受累大小和范围的分级系统,以预测在原发性翼状胬肉切除术中术中使用辅助性局部丝裂霉素-C(MMC)的患者的复发情况。
病例系列。
2005年至2010年,卡拉奇阿迦汗大学医院眼科。
120例男性患者(120只眼)采用裸巩膜法,使用浓度为0.2mg/ml(0.02%)的MMC,暴露时间为3分钟,进行翼状胬肉手术切除。根据翼状胬肉的分级对受试者进行分类。患者每隔3个月随访至少1年,记录任何复发情况。
随访1年时,翼状胬肉复发率为6.7%。翼状胬肉复发与年轻年龄无显著相关性(p = 0.14)。就诊时翼状胬肉角膜受累程度较高与复发显著相关(p = 0.01)。
这些结果表明,患者就诊时翼状胬肉分级较高会导致手术切除后复发率增加。因此,建议早期切除翼状胬肉以降低其复发率。