Sardesai S H, Mourant A J, Sivathandon Y, Farrow R, Gibbons D O
Royal Cornwall Hospital (Treliske), Truro, Cornwall.
Br Heart J. 1990 Apr;63(4):234-7. doi: 10.1136/hrt.63.4.234.
Phaeochromocytoma is rare and usually presents as paroxysmal or sustained hypertension; none the less, it can also cause severe acute pulmonary oedema in normotensive individuals. Six patients with phaeochromocytoma presenting in Cornwall and West Devon between 1982 and 1986 are described. Five of them died of pulmonary oedema within 24 hours of the onset of symptoms. At necropsy all five had normal sized hearts and in the four hearts examined by histology there was evidence of catecholamine induced heart disease in the form of focal myocardial necrosis. The sixth patient presented with arterial spasms and pulmonary oedema. Surgical removal of the causative tumour was successful in this patient.
嗜铬细胞瘤罕见，通常表现为阵发性或持续性高血压；尽管如此，它也可在血压正常的个体中引起严重的急性肺水肿。本文描述了1982年至1986年间在康沃尔郡和西德文郡出现的6例嗜铬细胞瘤患者。其中5例在症状出现后24小时内死于肺水肿。尸检时，所有5例患者的心脏大小均正常，在接受组织学检查的4例心脏中，有证据表明存在儿茶酚胺诱导的心脏病，表现为局灶性心肌坏死。第6例患者出现动脉痉挛和肺水肿。该患者通过手术成功切除了致病肿瘤。
