Department of Obstetrics and Gynecology, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical CenterTorrance, CA, USA.
Contraception. 2013 Jul;88(1):37-40. doi: 10.1016/j.contraception.2012.12.009. Epub 2013 Jan 2.
Potential pain with IUD insertion is a concern for women. Studies have found that systemic and local cervical therapies do not reduce pain scores. Since intrauterine infusion of lidocaine may reduce pain with endometrial aspiration, in this pilot study, we tested whether such infusion through an inexpensive endometrial aspirator could reduce IUD insertion pain scores with IUD insertion.
In this randomized, double-blinded, placebo control pilot study of 40 women undergoing IUD insertion, pain scores of women receiving 1.2 mL 2% lidocaine versus normal saline (1:1) infused 3 min prior to IUD insertion were measured using a 0-9-point scale.
Pain at tenaculum placement was similar between groups. There was no difference in mean pain scores during IUD insertion of women infused with lidocaine (2.95) versus normal saline (3.75), p=.37. Considerable variation in pain scores was noted; 46% of subjects had pain scores ≤2 while 33% had pain scores ≥5.
Use of 2% lidocaine administered through an endometrial aspirator did not significantly reduce IUD insertion pain scores in this pilot study.
宫内节育器（IUD）置入时的潜在疼痛是女性关注的问题。研究发现，全身和局部宫颈治疗并不能降低疼痛评分。由于宫内注射利多卡因可能会减轻子宫内膜抽吸时的疼痛，因此在这项初步研究中，我们测试了通过廉价的子宫内膜抽吸器进行宫内输注是否可以降低 IUD 置入时的疼痛评分。
在这项 40 名女性接受 IUD 置入的随机、双盲、安慰剂对照初步研究中，使用 0-9 分制测量在 IUD 置入前 3 分钟接受 1.2 毫升 2%利多卡因与生理盐水（1:1）输注的女性的疼痛评分。
两组在放置 Tenaculum 时的疼痛相似。接受利多卡因输注（2.95）与生理盐水输注（3.75）的女性在 IUD 置入期间的平均疼痛评分无差异，p=.37。疼痛评分的变化很大；46%的受试者疼痛评分≤2，而 33%的受试者疼痛评分≥5。
在这项初步研究中，通过子宫内膜抽吸器给予 2%利多卡因并没有显著降低 IUD 置入时的疼痛评分。
