囊性纤维化患者中幽门螺杆菌感染的流行率。
Prevalence of Helicobacter pylori infection in patients with cystic fibrosis.
机构信息
Department of Pediatric Gastroenterology and Metabolism, Poznań University of Medical Sciences, Szpitalna 27/33, 60-572 Poznań, Poland.
出版信息
J Cyst Fibros. 2013 Dec;12(6):761-5. doi: 10.1016/j.jcf.2013.01.004. Epub 2013 Feb 1.
INTRODUCTION
Helicobacter pylori (H. pylori) is one of the most common bacterial infections worldwide. The prevalence of Hp infection in cystic fibrosis (CF) is unclear. Thus, the aim of our study was to determine the prevalence of H. pylori infection in CF patients and to correlate H. pylori presence with CF expression.
MATERIAL AND METHODS
The presence of H. pylori infection was assessed using a breath test with isotope-labeled urea in CF 79 patients compared to 302 healthy control subjects (HS).
RESULTS
Fifteen (19.0%) CF patients were H. pylori positive. No statistical differences in the basic clinical parameters or in their distribution were documented. No clinical factor was an independent risk factor of H. pylori infection. The corrected prevalence of H. pylori infection in pediatric CF patients and HS was 14.4% and 9.8%, respectively.
CONCLUSION
The prevalence of H. pylori infection in CF patients is not different from that in healthy subjects.
简介
幽门螺杆菌（H. pylori）是全球最常见的细菌感染之一。囊性纤维化（CF）中 Hp 感染的流行情况尚不清楚。因此，我们的研究目的是确定 CF 患者中 H. pylori 感染的流行率，并将 H. pylori 的存在与 CF 的表达相关联。
材料和方法
使用同位素标记尿素的呼吸试验评估 79 例 CF 患者和 302 名健康对照者（HS）中 H. pylori 感染的存在情况。
结果
15 例（19.0%）CF 患者 H. pylori 阳性。未记录到基本临床参数或其分布存在统计学差异。没有临床因素是 H. pylori 感染的独立危险因素。经校正后，儿科 CF 患者和 HS 中 H. pylori 感染的患病率分别为 14.4%和 9.8%。
结论
CF 患者中 H. pylori 感染的流行率与健康人群无差异。
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