[Heterogeneity of platelet monoamine oxidase in man].

Multiplicity of platelet MAO was studied. Multiple forms of enzyme was separated with the use of 1.5% Tritone x-100 and, 1.3 M urea at pH 7.4 in, 0.01 M K-Na phosphate buffer. Three forms of MAO--MAO-I, MAO-II, and MAO-III were obtained under separation of solubilized proteins by affinity chromatography on AN-Sepharose 4B. Deprenyl in 10(-5) M inhibited all forms of the activity completely. Relation between multiple forms of the brain and platelet was discussed.