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开发一种在 MRI 中呈现宽视场视觉刺激的方法,用于周边视觉研究。

Development of a method to present wide-view visual stimuli in MRI for peripheral visual studies.

机构信息

Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan.

出版信息

J Neurosci Methods. 2013 Apr 15;214(2):126-36. doi: 10.1016/j.jneumeth.2013.01.021. Epub 2013 Feb 1.

Abstract

We developed a novel wide-view visual presentation system for fMRI studies. Computer-generated images were projected onto a hemispheric, translucent screen inside the MRI bore and were then back-projected onto a 52mm diameter screen. To achieve a wide field view, a spherical screen with a curvature radius of 30mm was placed 30mm away from the subjects' eyes. The subjects wore contact lenses that enabled them to focus on the screen, and the resulting visual field reached 120°. To evaluate the clarity and quality of the MRI images, a signal-to-noise ratio valuation experiment was performed. In addition, we successfully applied this visual presentation system to studies of visual retinotopic mapping and object perception neural function in the peripheral visual field. Our study demonstrated that the system is compatible with the MRI environment. Based on the wide-field mapping results, this system was more effective at mapping a checkerboard stimuli in V1-V3 from the central to peripheral visual fields. In higher-level visual areas, we successfully located several classical category-selective areas, including the face-selective area (FFA), occipital face area (OFA), house-selective area (PPA), transverse occipital sulcus (TOS), lateral occipital complex (LOC) and posterior fusiform area (pFs). In these areas, we found that the response amplitudes exhibited different decreasing trends with increasing eccentricity. In conclusion, we developed a simple, effective method for presenting wide-view visual stimuli within the MRI environment that can be applied to many kinds of fMRI studies of peripheral vision.

摘要

我们开发了一种新的 fMRI 研究宽视场视觉呈现系统。计算机生成的图像被投影到 MRI 磁体内部的一个半球形半透明屏幕上,然后再被反向投影到一个 52mm 直径的屏幕上。为了实现宽视场,我们将一个曲率半径为 30mm 的球形屏幕放置在离被试眼睛 30mm 的位置。被试佩戴接触镜,使他们能够将焦点对准屏幕,从而产生 120°的视场。为了评估 MRI 图像的清晰度和质量,我们进行了信噪比评估实验。此外,我们还成功地将这种视觉呈现系统应用于周边视觉视野中的视觉视网膜映射和物体感知神经功能的研究。我们的研究表明,该系统与 MRI 环境兼容。基于宽场映射结果,该系统在从中央到周边视野的 V1-V3 中对棋盘刺激进行映射更加有效。在更高层次的视觉区域中,我们成功定位了几个经典的类别选择区域,包括面部选择区域(FFA)、枕部面部区域(OFA)、房屋选择区域(PPA)、横向枕沟(TOS)、外侧枕叶复合体(LOC)和后部梭状回(pFs)。在这些区域中,我们发现随着离中心距离的增加,响应幅度呈现出不同的递减趋势。总之,我们开发了一种在 MRI 环境中呈现宽视场视觉刺激的简单、有效的方法,可应用于许多周边视觉 fMRI 研究。

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