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拉斯穆森脑炎

Rasmussen's encephalitis.

作者信息

Dawodu C O, Akinbo D D

机构信息

Department of Medicine, Lagos State College of Medicine (LASUCOM) and Teaching Hospital (LASUTH), Ikeja, Lagos, Nigeria.

出版信息

Niger J Clin Pract. 2013 Jan-Mar;16(1):113-5. doi: 10.4103/1119-3077.106780.

Abstract

BACKGROUND

Rasmussen's encephalitis is an uncommon chronic inflammatory disease disorder of unknown etiology.

OBJECTIVES

The aim of this report was to create an awareness of Rasmussen's encephalitis in our clinical practice in Africa.

MATERIALS AND METHODS

We searched online for literature on Rasmussen's encephalitis with an emphasis on documented cases in Africa and in blacks all over the world.

RESULTS

Master F.M., a 14-year-old male, presented with history of recurrent seizures on three occasions. The first was after an upper respiratory tract infection, the second was a post-complicated meningo-encephalitis and the third episode was associated with receptive aphasia, hemiparesis and intellectual impairment. Neuroimaging studies revealed cerebellar atrophy and infarction of territory of the middle cerebral artery. His electroencephalogram showed bi-frontal theta activity left>right and poly spikes left>>right, diagnostic of complex partial seizures. In a period of 12 months, his gait and speech had improved while his intellectual impairment permitted re-admission into a lower academic class. He is presently on phenytion and prednisolone tablets only.

CONCLUSION

Master F.M. had all the clinical features buttressed with neuroimaging results of a clinically probable Rasmussen's encephalitis. However, an advanced neuroimaging study is needed to detect and quantify hemispherical volume loss.

摘要

背景

拉斯穆森脑炎是一种病因不明的罕见慢性炎症性疾病。

目的

本报告旨在提高我们非洲临床实践中对拉斯穆森脑炎的认识。

材料与方法

我们在网上搜索有关拉斯穆森脑炎的文献,重点关注非洲及世界各地黑人中的记录病例。

结果

F.M. 少爷,一名14岁男性,有三次癫痫复发史。第一次是在上呼吸道感染后,第二次是在复杂性脑膜脑炎后,第三次发作伴有感觉性失语、偏瘫和智力障碍。神经影像学研究显示小脑萎缩和大脑中动脉供血区梗死。他的脑电图显示双侧额叶θ波活动左>右,多棘波左>>右,诊断为复杂部分性发作。在12个月的时间里,他的步态和言语有所改善,而他的智力障碍允许他重新进入较低的学术班级。他目前仅服用苯妥英和泼尼松龙片。

结论

F.M. 少爷具备所有临床特征,并得到了临床疑似拉斯穆森脑炎的神经影像学结果支持。然而,需要进行先进的神经影像学研究来检测和量化半球体积损失。

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