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散发性人类李斯特菌病患者分离的单核细胞增生李斯特菌 4b 血清型菌株中镉和砷抗性的遗传决定因素。

Genetic determinants for cadmium and arsenic resistance among Listeria monocytogenes serotype 4b isolates from sporadic human listeriosis patients.

机构信息

Department of Food, Bioprocessing & Nutrition Sciences, North Carolina State University, Raleigh, North Carolina, USA.

出版信息

Appl Environ Microbiol. 2013 Apr;79(7):2471-6. doi: 10.1128/AEM.03551-12. Epub 2013 Feb 1.

Abstract

In Listeria monocytogenes serotype 4b isolates from sporadic listeriosis, heavy metal resistance was primarily encountered in certain clonal groups (ECI, ECII, and ECIa). All arsenic-resistant isolates harbored the arsenic resistance cassette previously identified in pLI100; ECIa harbored additional arsenic resistance genes and a novel cadmium resistance determinant in a conserved chromosomal locus.

摘要

在来自散发性李斯特菌病的单核细胞增生李斯特菌 4b 血清型分离株中,重金属耐药性主要见于某些克隆群(ECI、ECII 和 ECIa)。所有耐砷的分离株均携带先前在 pLI100 中鉴定出的砷抗性盒;ECIa 还携带另外的砷抗性基因和一个新的镉抗性决定簇,位于保守的染色体位置。

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