Cancarevic Djajic Branka, Vilendecic Rade, Ecim-Zlojutro Vesna, Lucic Nenad, Draganovic Dragica, Savic Sasa
Clinic of Gynecology and Obstetrics, Clinical Center Banja Luka, Bosnia and Herzegovina.
Acta Inform Med. 2012 Dec;20(4):249-53. doi: 10.5455/aim.2012.20.249-253.
The purpose of each antenatal control focuses on the detection and prevention of hypoxic-ischemic injury and fetal death (1)) using modern biophysical tests and Doppler parameters.
This study examines the correlation of changes in arterial compared to venous hemodynamics of the fetus and is determined by the most sensitive and most specific Doppler parameter in the assessment of intrauterine fetal status.
The study was conducted as prospective and included 119 pregnant women. All subjects underwent NST (nonstres test), and Doppler measurements of blood flow in the umbilical artery (Aum), fetal aorta (Ao) and the central cerebral artery (MCA). In case of borderline and pathological arterial flow was measured through the ductus venozus (DV) and umbilical vein (VU). At birth to the child was determined umbilical artery blood pH and Apgar score (AS) in the first minute. Based on the clinical condition of the newborn and outcome was calculated perinatal morbidity and mortality.
In all cases with a pathological arterial flow, which is verified during measurement also the pathological venous flow and confirmed fetal acidemia at birth and low Apgar scores? In this group, the two neonates died in the first week.
There is a justification for the analysis of venous flow in the event borderline and pathologic findings in fetal arterial system. It has been proven that the cerebroumbilical (C/U) index is most effective parameter in predicting changes in the venous system and this the most sensitive Doppler parameter in predicting fetal acidosis and the most specific Doppler flow through the central cerebral artery.
每次产前检查的目的在于通过现代生物物理检测和多普勒参数来检测并预防缺氧缺血性损伤及胎儿死亡(1)。
本研究探讨胎儿动脉与静脉血流动力学变化的相关性,并由评估宫内胎儿状况时最敏感且最具特异性的多普勒参数来确定。
本研究为前瞻性研究,纳入了119名孕妇。所有受试者均接受了无应激试验(NST),并对脐动脉(Aum)、胎儿主动脉(Ao)和大脑中动脉(MCA)的血流进行了多普勒测量。若动脉血流处于临界值及病理状态,则测量静脉导管(DV)和脐静脉(VU)的血流。出生时测定新生儿脐动脉血pH值及1分钟阿氏评分(AS)。根据新生儿的临床状况计算围产期发病率和死亡率。
在所有动脉血流呈病理状态的病例中,测量时也证实了静脉血流病理状态,并在出生时确诊胎儿酸血症及阿氏评分较低。在该组中,有两名新生儿在第一周死亡。
在胎儿动脉系统出现临界值及病理结果时,分析静脉血流是合理的。已证实脑脐(C/U)指数是预测静脉系统变化最有效的参数,也是预测胎儿酸中毒最敏感的多普勒参数以及大脑中动脉最具特异性的多普勒血流参数。