Kim Hee Sung, Kim Beom Su, Lee In Seob, Lee Sol, Yook Jeoung Hwan, Kim Byung Sik
Department of Gastric Surgery, Asan Medical Center, Ulsan University School of Medicine, Seoul, Korea.
J Laparoendosc Adv Surg Tech A. 2013 Apr;23(4):323-31. doi: 10.1089/lap.2012.0389. Epub 2013 Feb 4.
The technique of totally laparoscopic total gastrectomy (TLTG) has been developed for gastric cancer, but its feasibility and surgical outcomes remain unclear. This is the first study comparing the early surgical outcomes of TLTG with those of conventional open total gastrectomy (OTG) for gastric cancer.
Between January 2011 and December 2011, 139 patients underwent TLTG, and 207 patients underwent OTG for gastric cancer; surgical procedures were selected by means of preoperative diagnostic tests under T3N2M0. Clinicopathologic characteristics and early surgical outcomes in the two groups were compared retrospectively.
There were no significant difference in preoperative characteristics between the two groups, and the durations of surgery were not significantly different. However, TLTG was superior to OTG in terms of time to first flatus, time to commencement of soft diet, pain score (visual analog scale), need for analgesics, length of hospital stay, and overall postoperative complications (each P<.05). The median number of lymph nodes harvested was significantly higher in the TLTG group (37 versus 34; P=.039). Resection margins were negative in all patients.
TLTG should be considered as a safe and practicable alternative to OTG for the treatment of gastric cancer. Moreover, it is less invasive and results in faster recovery than OTG.
全腹腔镜全胃切除术(TLTG)技术已用于胃癌治疗,但其可行性和手术效果仍不明确。这是第一项比较TLTG与传统开放全胃切除术(OTG)治疗胃癌早期手术效果的研究。
2011年1月至2011年12月期间,139例患者接受了TLTG治疗胃癌,207例患者接受了OTG治疗胃癌;手术方式根据T3N2M0期术前诊断检查结果选择。对两组患者的临床病理特征及早期手术效果进行回顾性比较。
两组患者术前特征无显著差异,手术时间也无显著差异。然而,在首次排气时间、开始进软食时间、疼痛评分(视觉模拟评分)、镇痛需求、住院时间及术后总体并发症方面,TLTG优于OTG(各P<0.05)。TLTG组清扫淋巴结的中位数显著高于OTG组(37枚对34枚;P=0.039)。所有患者切缘均为阴性。
TLTG应被视为治疗胃癌的一种安全可行的替代OTG的方法。此外,与OTG相比,它的侵袭性更小,恢复更快。