Hematology Department, Hospital de São João, Porto, Portugal.
Clin Drug Investig. 2013 Feb;33 Suppl 1:S19-21. doi: 10.1007/s40261-012-0014-4.
Mucormycosis is a rare, highly aggressive and usually fatal infection, which affects immunocompromised patients. This case report describes a patient with acute promyelocytic leukemia who received antifungal therapy for a suspected pulmonary Aspergillus infection. Material from a lobectomy suggested that on histologic grounds the diagnosis had to be changed to mucormycosis. High suspicion of a Mucor infection favors early detection and timely appropriate antifungal therapy, which is crucial for the prognosis of these patients.
毛霉病是一种罕见的、侵袭性很强且通常致命的感染,影响免疫功能低下的患者。本病例报告描述了一位患有急性早幼粒细胞白血病的患者,该患者因疑似肺部曲霉菌感染接受了抗真菌治疗。肺叶切除标本提示,从组织学角度来看,必须将诊断改为毛霉病。高度怀疑毛霉感染有利于早期发现和及时适当的抗真菌治疗,这对这些患者的预后至关重要。