Popko Magdalena, Kacalak-Rzepka Anna, Bielecka-Grzela Stanisława, Wesołowska Jolanta, Klimowicz Adam, Maleszka Romuald
Katedra i Klinika Chorób Skórnych i Wenerycznych Pomorskiego Uniwersytetu Medycznego w Szczecinie, al. Powstańców Wlkp. 72, 70-111 Szczecin.
Ann Acad Med Stetin. 2011;57(3):23-7.
Vitiligo is an idiopathic chronic skin disease that is notable for depigmented macules forming by destruction of melanocytes mediated by cells of the immune system. Vitiligo occurs in 1-2% of the population irrespective of race and without predilection to gender or age. The dynamics and extent of the disease vary widely, ranging from stable cases with isolated minor foci to states showing rapid progression and occupying large areas of the skin. For many patients, the disease represents a serious cosmetic defect which limits their activities in various spheres of life. There are many noninvasive methods of treatment but none of them offers a guarantee of complete therapeutic success. PUVA- and UVB-therapy are recognized as the most effective and most commonly used methods. The management of vitiligo should also include education, cosmetic correction options, and psychotherapy in some cases.
白癜风是一种特发性慢性皮肤病，其显著特征是由免疫系统细胞介导的黑素细胞破坏形成色素脱失斑。白癜风在1%-2%的人群中发病，与种族无关，无性别或年龄倾向。该病的动态变化和范围差异很大，从仅有孤立小病灶的稳定病例到显示快速进展且累及大面积皮肤的状态。对许多患者而言，该病是一种严重的美容缺陷，限制了他们在生活各个领域的活动。有许多非侵入性治疗方法，但没有一种能保证完全治愈成功。补骨脂素加紫外线A照射疗法（PUVA）和紫外线B照射疗法被认为是最有效且最常用的方法。白癜风的治疗还应包括教育、美容矫正选择，以及在某些情况下的心理治疗。
