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马拉维一家门诊诊所中出现的小儿心脏疾病谱。

The spectrum of paediatric cardiac disease presenting to an outpatient clinic in Malawi.

作者信息

Kennedy Neil, Miller Paul

机构信息

Department of Paediatrics and Child Health, University of Malawi, P/Bag 360 Chichiri, Blantyre 3, Malawi.

出版信息

BMC Res Notes. 2013 Feb 7;6:53. doi: 10.1186/1756-0500-6-53.

Abstract

BACKGROUND

As progress is made towards attaining Millennium Development Goal 4, further reductions in paediatric mortality will only be achieved by concentrating on the burden of non-communicable or neglected diseases. The literature relating to paediatric cardiac disease in sub-Saharan Africa is sparse. There are no published descriptions of paediatric cardiac disease from Malawi, making it impossible to estimate the contribution it makes to childhood morbidity and mortality.

FINDINGS

In 2008, a paediatric cardiac clinic with echocardiogram scanning was established in Blantyre, southern Malawi. Between January 2009 and February 2011, the age and cardiac diagnosis of every child with an abnormal echocardiogram was recorded in a database. Of 250 children, 139 (55.6%) had congenital heart disease, and 111 (44.4%) acquired heart disease. Ventricular septal defect (VSD) (24%), Tetralogy of Fallot (10%) and patent ductus arteriousus (7.2%) were the commonest forms of congenital heart disease. Rheumatic heart disease (RHD) (22.4%) and dilated cardiomyopathy (13.6%) were the commonest acquired diseases. The mean age of presentation was 3 years 2 months for VSD and 11 years 6 months for RHD.

CONCLUSIONS

In this cohort of children from one centre in Malawi, acquired heart disease - in particular rheumatic heart disease was almost as common as congenital heart disease. Most presented late. It is likely that untreated cardiac disease causes a large number of childhood deaths in Malawi. In addition to renewing secondary preventative efforts against rheumatic heart disease, adequate and accessible cardiothoracic surgical services should be established at a regional level.

摘要

背景

随着在实现千年发展目标4方面取得进展,只有集中关注非传染性疾病或被忽视疾病的负担,才能进一步降低儿童死亡率。撒哈拉以南非洲地区有关小儿心脏病的文献稀少。马拉维没有关于小儿心脏病的公开描述,因此无法估计其对儿童发病率和死亡率的影响。

研究结果

2008年,在马拉维南部的布兰太尔建立了一个配备超声心动图扫描设备的小儿心脏诊所。2009年1月至2011年2月期间,对每例超声心动图异常儿童的年龄和心脏诊断结果都记录在一个数据库中。在250名儿童中,139名(55.6%)患有先天性心脏病,111名(44.4%)患有后天性心脏病。室间隔缺损(VSD)(24%)、法洛四联症(10%)和动脉导管未闭(7.

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