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喀麦隆农村地区风湿性瓣膜病的发生率、模式及随访:希松医院的经验

Rheumatic valvulopathies occurence, pattern and follow-up in rural area: the experience of the Shisong Hospital, Cameroon.

作者信息

Tantchou Tchoumi J C, Butera G

机构信息

St. Elizabeth Catholic General Hospital, Shisong, P.O. Box 8 Kumbo, Cameroun.

出版信息

Bull Soc Pathol Exot. 2009 Aug;102(3):155-8.

Abstract

UNLABELLED

Rheumatic heart disease (RHD) remains a major public health problem in developing countries. Whereas Africa has 10% of the world's population, broadly as many as half of the 2.4 million children affected by RHD live on the continent. We report on the occurrence and pattern of valve involvement in RHD using echocardiography in our centre and post surgical follow-up.

METHODS

In this retrospective study, transthoracic echocardiography (TTE) data collected from the Shisong cardiac centre over a period of 24 months (August 2005 to August 2007) were reviewed. Patients with a precordial murmur were selected. A total of 262 echocardiographic examinations were done in the centre over the two-year study period. The screening allowed us to see two categories of patients: 169 (64.5%), 79 male and 90 female, out of the 262 patients with abnormal results had an echocardiographic diagnosis of RHD, 80 (30.5%) patients had congenital heart disease. The 13 (5%) patients left had innocent murmur. Mitral valve regurgitation was the commonest echocardiographic diagnosis present in 101 patients (59.7%). Thirty-six (13.7%) patients had mixed mitral valve disease, 40 (23.7%) had mixed aortic and mitral valve disease, 42 (25%) had pure mitral stenosis and 26 (15.3%) had pure aortic regurgitation. The complications of RHD being observed included secondary pulmonary hypertension in 20 patients (11.8%) and functional tricuspid regurgitation was seen in 39 (21.9%). The congenital heart disease were: tetralogy of Fallot 29.1%, isolated ventricular septal defect 62.5%, isolated atrial septal defect 3.2%, atrioventricular canal 1.1%, patent ductus arteriosus 2.2%, common arterial trunk 1.9%. Our data showed that in children above 10-years-old in rural zone of Cameroon presenting with a precordial murmur RHD has to be suspected. Acute rheumatic fever primary and secondary prevention as well as rheumatic fever registers are important for the disease eradication in our countries. More surgical centres for a better management of the RHD complications are needed in sub-Saharan Africa. Due to poverty and illiteracy of parents, the post surgical follow up of patients is challenging.

摘要

未标注

风湿性心脏病(RHD)在发展中国家仍然是一个主要的公共卫生问题。非洲占世界人口的10%,但受风湿性心脏病影响的240万儿童中,多达一半生活在非洲大陆。我们报告了在我们中心使用超声心动图以及术后随访中风湿性心脏病瓣膜受累的发生情况和模式。

方法

在这项回顾性研究中,对从希松心脏中心在24个月期间(2005年8月至2007年8月)收集的经胸超声心动图(TTE)数据进行了回顾。选择有心前区杂音的患者。在为期两年的研究期间,该中心共进行了262次超声心动图检查。筛查使我们看到两类患者:262例检查结果异常的患者中,169例(64.5%),男性79例,女性90例,经超声心动图诊断为风湿性心脏病,80例(30.5%)患者患有先天性心脏病。剩下的13例(5%)患者有生理性杂音。二尖瓣反流是最常见的超声心动图诊断,101例患者(59.7%)存在该情况。36例(13.7%)患者有二尖瓣混合病变,40例(23.7%)有主动脉瓣和二尖瓣混合病变,42例(25%)有单纯二尖瓣狭窄,26例(15.3%)有单纯主动脉瓣反流。观察到的风湿性心脏病并发症包括20例患者(11.8%)出现继发性肺动脉高压和39例(21.9%)出现功能性三尖瓣反流。先天性心脏病包括:法洛四联症29.1%,孤立性室间隔缺损62.5%,孤立性房间隔缺损3.2%,房室通道1.1%,动脉导管未闭2.2%,共同动脉干1.9%。我们的数据表明,在喀麦隆农村地区出现心前区杂音的10岁以上儿童中,必须怀疑患有风湿性心脏病。急性风湿热的一级和二级预防以及风湿热登记对于我们国家根除该疾病很重要。撒哈拉以南非洲需要更多的外科中心来更好地管理风湿性心脏病并发症。由于父母贫困和文盲,对患者进行术后随访具有挑战性。

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