Kim Sae Byol, Lee Soohyeon, Koh Myoung Ju, Lee In Seon, Moon Chan Soo, Jung Sung Mo, Kang Young Ae
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Tuberc Respir Dis (Seoul). 2013 Jan;74(1):32-6. doi: 10.4046/trd.2013.74.1.32. Epub 2013 Jan 31.
A 43-year-old woman with breast cancer who was on neoadjuvant chemotherapy presented with cough, sputum and mild fever. High-resolution computed tomography showed diffuse ground glass opacities in bilateral lungs and subpleural patchy consolidations. Initially, she was thought to have pneumonia or interstitial lung diseases such as drug-induced pneumonitis and treated with antibiotics and steroids. She subsequently got breast cancer surgery because of disease progression, and concurrent thoracoscopic lung biopsy revealed metastatic carcinoma of the lung from breast cancer. The diagnosis of suspected interstitial lung disease can be made without lung biopsy, but malignancy should always be considered and lung biopsy should be performed in the absence of a definitive clinical diagnosis.
一名正在接受新辅助化疗的43岁乳腺癌女性出现咳嗽、咳痰和低热症状。高分辨率计算机断层扫描显示双肺弥漫性磨玻璃影和胸膜下斑片状实变。起初,她被认为患有肺炎或间质性肺疾病,如药物性肺炎,并接受了抗生素和类固醇治疗。随后,由于疾病进展,她接受了乳腺癌手术,同期胸腔镜肺活检显示为乳腺癌肺转移癌。疑似间质性肺疾病的诊断可以在不进行肺活检的情况下做出,但应始终考虑恶性肿瘤的可能,在没有明确临床诊断的情况下应进行肺活检。