散发性前弹力层营养不良角膜共焦显微镜检查结果。
Corneal confocal microscopy findings in sporadic cases of pre-descemet corneal dystrophy.
机构信息
Institute of Vision and Optics (G.A.K., G.D.K., V.P.K., A.G.P., A.I.P.), University of Crete, Crete, Greece; and Sai Surya Eye Care (V.P.K.), Maharashtra, India.
出版信息
Eye Contact Lens. 2014 Mar;40(2):e8-e12. doi: 10.1097/ICL.0b013e318273be9f.
PURPOSE
To present corneal confocal microscopy (CCM) findings in a series of patients with pre-Descemet corneal dystrophy (PDCD).
METHODS
A 28-year-old man, a 50-year-old man, a 30-year-old woman, and a 31-year-old man were clinically diagnosed with PDCD on slit lamp microscopic evaluation. All patients were evaluated by means of CCM. The parents of the patients were clinically evaluated. Two of the patients underwent photorefractive keratectomy.
RESULTS
In all the patients, CCM revealed highly reflective stromal particles and pleomorphic structures that included particles in the deep stroma, immediately anterior to the Descemet membrane extending up to 60 μm from endothelium. No evidence of PDCD was observed clinically in the parents of the patients. Postoperative course of photorefractive keratectomy was uneventful for both of the patients.
CONCLUSIONS
With the use of CCM, a specific pattern of findings seemed to be related with PDCD in this series of sporadic cases.
目的
介绍一系列伴有前弹力层角膜营养不良（PDCD）患者的角膜共焦显微镜（CCM）检查结果。
方法
对 1 名 28 岁男性、1 名 50 岁男性、1 名 30 岁女性和 1 名 31 岁男性在裂隙灯显微镜检查评估时临床诊断为 PDCD。对所有患者均采用 CCM 进行评估。对患者的父母进行临床评估。其中 2 名患者接受了准分子激光屈光性角膜切削术。
结果
在所有患者中，CCM 均显示出高度反光的基质颗粒和多种形态的结构，包括深基质中的颗粒、紧邻前弹力膜延伸至内皮 60μm 处的颗粒。患者父母的临床检查均未发现 PDCD 的证据。两名患者的准分子激光屈光性角膜切削术术后过程均无异常。
结论
在这一系列散发病例中，使用 CCM 似乎可以发现与 PDCD 相关的特定表现模式。
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