Achiron A, Gornish M, Melamed E
Department of Neurology, Beilinson Medical Center, Petach-Tiqva, Israel.
Stroke. 1990 May;21(5):817-9. doi: 10.1161/01.str.21.5.817.
We describe a 42-year-old woman who developed superior sagittal and left transverse sinus thrombosis associated with prolonged epsilon-aminocaproic acid therapy for menorrhagia. This antifibrinolytic agent has been used in women with menorrhagia to promote clotting and reduce blood loss. Although increased risk of thromboembolic disease has been reported during treatment with epsilon-aminocaproic acid, cerebral sinus thrombosis has not been previously described. Careful use of epsilon-aminocaproic acid therapy is recommended.
我们描述了一名42岁女性，她因月经过多接受了长时间的氨甲环酸治疗，随后发生了上矢状窦和左侧横窦血栓形成。这种抗纤维蛋白溶解剂已被用于月经过多的女性，以促进凝血并减少失血。虽然已有报道称在使用氨甲环酸治疗期间血栓栓塞性疾病的风险增加，但此前尚未有脑窦血栓形成的描述。建议谨慎使用氨甲环酸治疗。
