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[恶性膀胱后神经鞘瘤导致上尿路梗阻。治疗策略]

[Obstruction of the upper urinary tract caused by a malignant retrovesicular schwannoma. Therapeutic strategy].

作者信息

González Enguita C, Caro Cebrián C, Gil Sanz M J, Rodríguez Vela L, Valero Palomero I, Roncalés Badal A, Rioja Sanz C, Rioja Sanz L A

机构信息

Servicios de Urología, Hospital Miguel Servet, Zaragoza.

出版信息

Actas Urol Esp. 1990 Jan-Feb;14(1):46-9.

PMID:2339652
Abstract

We present a case of malignant Schwannoma (MS) of uncommon, retroperitoneal and retrovesical localization in a 42-year-old male, which provoked bilateral ureteral obstruction as a urological manifestation. We show our therapeutic strategy by means of a schedule of systemic neoadjuvant chemotherapy with vincristine, adriamycin, cyclophosphamide, decarbacine combined with exeresis and urinary continuity reconstruction surgery. We point out that it is a low incidence but highly aggressive tumour and that treatment continues to be local radical excision, whilst chemotherapy probably continues to have little value.

摘要

我们报告一例42岁男性患者,患有罕见的腹膜后和膀胱后恶性神经鞘瘤(MS),该肿瘤引发双侧输尿管梗阻,作为泌尿系统表现。我们通过长春新碱、阿霉素、环磷酰胺、氮烯咪胺联合全身新辅助化疗方案结合手术切除和尿路连续性重建手术展示了我们的治疗策略。我们指出,这是一种发病率低但侵袭性高的肿瘤,治疗仍以局部根治性切除为主,而化疗可能仍然价值不大。

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