Kuiper Jesse W P, Brohet Richard M, Wassink Sander, van den Bekerom Michel P J, Nolte Petrus A, Vergroesen Diederik A
Department of Orthopaedics, Spaarne Hospital, Spaarnepoort 1, Hoofddorp, The Netherlands.
Hip Int. 2013 Mar-Apr;23(2):173-80. doi: 10.5301/HIP.2013.10612. Epub 2013 Jan 22.
We evaluated a prosthesis-retaining treatment protocol for prosthetic joint infection in patients presenting at a mean of 116 days (range 10-1216 days) after primary arthroplasty. Our regime involved irrigation and debridement followed by implantation of biodegradable gentamicin loaded sponges which do not require removal after implantation. Of 34 patients with a deep infection after total hip arthroplasty, Twenty-five were treated successfully, with a mean follow-up of 35 months. There were no permanent complications. This success rate is comparable to earlier studies. Early initiation of treatment demonstrated a tendency for better results, and late chronic infections had a worse outcome. Because the sponges are degradable, a number of further surgical procedures were avoided.
我们评估了一种用于人工关节感染的保留假体治疗方案，这些患者在初次关节置换术后平均116天（范围为10 - 1216天）前来就诊。我们的治疗方案包括冲洗和清创，随后植入可生物降解的载有庆大霉素的海绵，植入后无需取出。在34例全髋关节置换术后发生深部感染的患者中，25例治疗成功，平均随访35个月。无永久性并发症。该成功率与早期研究相当。早期开始治疗显示出结果更好的趋势，而晚期慢性感染的结果更差。由于海绵是可降解的，避免了一些进一步的外科手术。
