Whiteley P F, Oláh K S
Department of Obstetrics and Gynecology, Horton General Hospital, Banbury, Oxfordshire, England.
Am J Obstet Gynecol. 1990 May;162(5):1272-7. doi: 10.1016/0002-9378(90)90035-6.
Eighty patients with cervical abnormalities that were proved by colposcopy were treated with the low-voltage diathermy loop by excision biopsy of isolated lesions (n = 14), excision of the transformation zone (n = 52), or by cone biopsy (n = 14). Treatment was performed at the time of initial assessment with the patient under a local anesthetic. Treatment proved acceptable to patients and minimal discomfort was reported. Primary hemorrhage was not a problem, although secondary hemorrhage occurred in 3.7% of patients. Excision was histologically complete in 85% of cases, and excision was clinically complete in the remaining cases. Diathermy coagulation to the base of the lesion ensured hemostasis and destroyed any residual cervical intraepithelial neoplasia. Follow-up cytologic findings were normal in 91% of patients at 3 months, and colposcopy showed no abnormality in 95% of patients at 6 months. The squamocolumnar junction was fully visible in 91% of patients. Thus excisional techniques with the low-voltage diathermy loop appear to be a viable treatment option for cervical intraepithelial neoplasia.
80例经阴道镜检查证实有宫颈异常的患者接受了低压电凝圈套切除术，其中孤立性病变切除活检14例，转化区切除52例，锥形活检14例。治疗在初次评估时进行，患者在局部麻醉下接受治疗。患者对治疗表示认可，报告的不适感最小。原发性出血不是问题，尽管3.7%的患者出现了继发性出血。85%的病例切除在组织学上是完整的，其余病例切除在临床上是完整的。对病变基底进行电凝确保了止血，并破坏了任何残留的宫颈上皮内瘤变。3个月时91%的患者随访细胞学检查结果正常，6个月时95%的患者阴道镜检查无异常。91%的患者鳞柱交界完全可见。因此，低压电凝圈套切除技术似乎是治疗宫颈上皮内瘤变的一种可行选择。
