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[外周动脉闭塞性疾病患者围手术期心肌缺血]

[Perioperative myocardial ischemia in patients with peripheral arterial occlusive diseases].

作者信息

Rapp H J, Buselmeier P, Gasteiger P, Hoberg E, Striebel J P

机构信息

Institut für Anaesthesiologie und Operative Intensivmedizin am Klinikum der Stadt Mannheim, Fakultät für Klinische Medizin, Universität Heidelberg.

出版信息

Anaesthesist. 1990 Apr;39(4):217-21.

PMID:2339773
Abstract

Patients with peripheral vascular disease (PVD) often have coronary artery disease (CAD) which means an increased risk during anesthesia. The prevalence of CAD is nearly 50% among such patients. Owing to claudication, diagnostic stress tests can rarely be performed in PVD patients. In order to evaluate the frequency of transient perioperative myocardial ischemia, Holter monitoring was performed in 30 consecutive PVD patients with ASA II-III and AVK scale (Fontaine) II-IV who were undergoing femoropopliteal bypass surgery. Patients who had left bundle branch block and left ventricular hypertrophy or were taking digitalis medication were excluded from Holter monitoring. The ST-segment analysis of the frequency modulated recordings (n = 19) revealed episodes of myocardial ischemia in 26% of the patients. Most (75%) of the episodes occurred preoperatively, and 25%, during or after the anesthesia or during preparation for it. Risk factors for CAD were more often found in patients with ST segment alterations than in patients without ST segment deviations, even though the preoperative antianginal medication administered was comparable in the two subgroups. It is concluded that in a considerable subset of PVD patients silent myocardial ischemia occurs, which can be related to the different perioperative intervals by means of ST segment analyses of Holter recordings. The ST segment may allow a better insight into the cardiac state of PVD patients. Further studies are necessary in larger populations to test our suspicion.

摘要

外周血管疾病(PVD)患者常伴有冠状动脉疾病(CAD),这意味着麻醉期间风险增加。此类患者中CAD的患病率近50%。由于间歇性跛行,PVD患者很少能进行诊断性应激试验。为了评估围手术期短暂性心肌缺血的发生率,对30例连续接受股腘动脉搭桥手术、ASA II - III级且AVK量表(Fontaine)II - IV级的PVD患者进行了动态心电图监测。有左束支传导阻滞、左心室肥厚或正在服用洋地黄药物的患者被排除在动态心电图监测之外。对调频记录(n = 19)的ST段分析显示,26%的患者出现心肌缺血发作。大多数发作(75%)发生在术前,25%发生在麻醉期间或之后或麻醉准备期间。即使两个亚组术前使用的抗心绞痛药物相当,但ST段改变的患者比无ST段偏差的患者更常发现CAD危险因素。结论是,在相当一部分PVD患者中发生了无症状心肌缺血,通过动态心电图记录的ST段分析可将其与不同的围手术期时间段相关联。ST段可能有助于更好地了解PVD患者的心脏状况。有必要在更大规模人群中进行进一步研究以验证我们的怀疑。

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