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用于预测肺动脉高压的定性超声心动图参数。

Qualitative echocardiography parameters for prediction of pulmonary hypertension.

作者信息

Lange T J, Baumgartner S, Arzt M, Pfeifer M

机构信息

Division of Pneumology, Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany.

出版信息

Int J Clin Pract Suppl. 2013 May(179):5-12. doi: 10.1111/ijcp.12068. Epub 2013 Feb 12.

Abstract

BACKGROUND

Current guidelines recommend echocardiography as the preferred screening method for pulmonary hypertension (PH). The probability of PH is primarily assessed by estimating the right ventricular systolic pressure while the value of qualitative parameters is uncertain. The aim of our study was to evaluate the diagnostic yield of qualitative and quantitative parameters from routine echocardiography reports for PH diagnosis.

METHODS

Consecutive patients with suspected PH who received right heart catheterisation and echocardiography within 2 weeks between April 2003 and September 2008 were retrospectively included. PH was diagnosed by a mean pulmonary artery pressure of ≥ 25 mmHg on right heart catheterisation. Qualitative and quantitative parameters from echocardiography reports were analysed with respect to their predictive value for PH diagnosis.

RESULTS

Inclusion criteria were met by 272 patients. Diagnosis of PH was confirmed in 172 and excluded in 100 patients. Qualitative and quantitative information about the right ventricle was available in 93% and 85% of the echocardiography reports respectively. Qualitative descriptions of the right ventricle to be dilated predicted PH with sensitivity, specificity, negative and positive predictive value of 89%, 63%, 78% and 80% respectively. An estimated right ventricular systolic pressure of ≥ 50 mmHg on echocardiography predicted PH with sensitivity, specificity, negative and positive predictive value of 84%, 69%, 68% and 84% respectively.

CONCLUSION

Qualitative parameters are frequently described in routine echocardiography reports and are valuable for the prediction of PH with a similar diagnostic accuracy as the estimation of right ventricular systolic pressure.

摘要

背景

当前指南推荐超声心动图作为肺动脉高压(PH)的首选筛查方法。PH的可能性主要通过估计右心室收缩压来评估,而定性参数的价值尚不确定。我们研究的目的是评估常规超声心动图报告中的定性和定量参数对PH诊断的诊断价值。

方法

回顾性纳入2003年4月至2008年9月期间连续2周内接受右心导管检查和超声心动图检查的疑似PH患者。通过右心导管检查时平均肺动脉压≥25 mmHg诊断为PH。分析超声心动图报告中的定性和定量参数对PH诊断的预测价值。

结果

272例患者符合纳入标准。172例确诊为PH,100例排除。分别有93%和85%的超声心动图报告提供了关于右心室的定性和定量信息。右心室扩大的定性描述预测PH的敏感性、特异性、阴性和阳性预测值分别为89%、63%、78%和80%。超声心动图估计右心室收缩压≥50 mmHg预测PH的敏感性、特异性、阴性和阳性预测值分别为84%、69%、68%和84%。

结论

常规超声心动图报告中经常描述定性参数,对于预测PH很有价值,其诊断准确性与估计右心室收缩压相似。

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