Department of Trauma Surgery, University Hospitals Leuven, Belgium.
Injury. 2013 Jul;44(7):964-8. doi: 10.1016/j.injury.2013.01.029. Epub 2013 Feb 8.
The management of hemodynamically unstable patients with severe pelvic fractures remains a challenge. Various treatment strategies have been advocated. This study analyzed the value of transcatheter angiographic embolization (TAE) for persistent haemodynamic instability after initial fracture stabilization.
From January 2002 to July 2011, 803 patients were identified with pelvic fractures, 295 of them (37%) were presenting with unstable pelvic fractures. Fifteen patients, all with unstable fractures (2%), remained hypotensive (systolic blood pressure<90 mmHg) despite adequate fluid resuscitation and emergent surgical fracture stabilization, subsequently underwent TAE.
The median age in the TAE-group was 57.9 years±20.12 (min 22; max 82) and the median ISS (injury severity score) was 35.8±11.7 (min 22; max 66). 13 out of 15 patients (87%) received initial external fixation and 2 patients (13%) where treated with a C-Clamp before TAE. Radiological success, defined as absence of contrast extravasation on completion angiography, was observed in all 15 patients. In total 3 (20%) patients died during the period of hospitalization, none of them owing to persistent or recurrent pelvic haemorrhage. In the remaining 12 patients, no early or late complications of TAE were identified. Preperitoneal pelvic packing was performed in two patients, both had open pelvic fractures.
TAE is a safe and very efficient procedure to treat persistent haemorrhage in patients with unstable pelvic fractures initially treated by surgical fracture stabilization procedures. On the long term, no early or late bleeding recurrence could be demonstrated with an overall survival rate of 80%. Preperitoneal pelvic packing can be reserved for patients with open fractures and active bleeding.
血流动力学不稳定的严重骨盆骨折患者的处理仍然是一个挑战。各种治疗策略已经被提出。本研究分析了经导管血管造影栓塞(TAE)在初始骨折稳定后持续血流动力学不稳定患者中的价值。
从 2002 年 1 月至 2011 年 7 月,共确定了 803 例骨盆骨折患者,其中 295 例(37%)为不稳定骨盆骨折。15 例患者(所有为不稳定骨折患者,2%)尽管进行了充分的液体复苏和紧急手术骨折稳定,但仍存在低血压(收缩压<90mmHg),随后进行了 TAE。
TAE 组的中位年龄为 57.9 岁±20.12(最小 22;最大 82),ISS(损伤严重程度评分)中位数为 35.8±11.7(最小 22;最大 66)。15 例患者中的 13 例(87%)接受了初始外固定,2 例(13%)在 TAE 前接受了 C 型夹治疗。所有 15 例患者均完成血管造影显示无造影剂外渗,即影像学成功。15 例患者中有 3 例(20%)在住院期间死亡,均非由于持续性或复发性骨盆出血。在其余 12 例患者中,未发现 TAE 的早期或晚期并发症。2 例患者进行了腹膜前骨盆填塞,均为开放性骨盆骨折。
TAE 是治疗初始手术骨折稳定治疗后血流动力学不稳定的骨盆骨折患者持续性出血的一种安全且非常有效的方法。在长期随访中,没有证据表明有早期或晚期出血复发,总体生存率为 80%。腹膜前骨盆填塞可保留用于开放性骨折和有活动性出血的患者。