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大鼠上丘损伤后的听觉定向与检测

Auditory orienting and detection in rats following lesions of the superior colliculus.

作者信息

Milner A D, Taylor M J

机构信息

Department of Psychology, University of St. Andrews, Fife, Scotland, U.K.

出版信息

Behav Brain Res. 1990 Mar 26;37(3):293-6. doi: 10.1016/0166-4328(90)90141-z.

DOI:10.1016/0166-4328(90)90141-z
PMID:2340103
Abstract

Rats were trained to run towards a lighted target following either bilateral lesions of the superior colliculus (SC) or control lesions of the overlying cortex. At 4 months post-surgery, the animals were tested for the disruptive effects of an auditory tone. An increase in running times was found in both groups, attributable to frequent freezing reactions in all animals. However, only the control rats made orienting reactions to the tones. It is argued that the freezing responses show that the SC lesions did not impair sensory detection; consequently, the orienting failure cannot be attributed to a sensory deficit.

摘要

大鼠在双侧上丘(SC)损伤或覆盖皮质的对照损伤后,被训练跑向一个明亮的目标。术后4个月,对动物进行听觉音调干扰效应测试。两组动物的奔跑时间均增加,这归因于所有动物频繁的僵住反应。然而,只有对照大鼠对音调做出定向反应。有人认为,僵住反应表明上丘损伤并未损害感觉检测;因此,定向失败不能归因于感觉缺陷。

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